Resveratrol—a boon for treating Alzheimer's disease?

TS Anekonda - Brain research reviews, 2006 - Elsevier
Resveratrol, a red wine polyphenol, is known to protect against cardiovascular diseases and
cancers, as well as to promote antiaging effects in numerous organisms. It also modulates …

Mitochondrial dysfunction and glaucoma

GYX Kong, NJ Van Bergen, IA Trounce… - Journal of …, 2009 - journals.lww.com
Glaucoma is increasingly recognized as a neurodegenerative disorder, characterized by the
accelerated loss of retinal ganglion cells (RGCs) and their axons. Open angle glaucoma …

Neuroprotective effects of anthocyanin-and proanthocyanidin-rich extracts in cellular models of Parkinson׳ s disease

KE Strathearn, GG Yousef, MH Grace, SL Roy… - Brain research, 2014 - Elsevier
Neuropathological evidence indicates that dopaminergic cell death in Parkinson׳ s disease
(PD) involves impairment of mitochondrial complex I, oxidative stress, microglial activation …

α-Synuclein is differentially expressed in mitochondria from different rat brain regions and dose-dependently down-regulates complex I activity

G Liu, C Zhang, J Yin, X Li, F Cheng, Y Li, H Yang… - Neuroscience …, 2009 - Elsevier
α-Synuclein (α-Syn) abnormality and mitochondrial deficiency are two major changes in the
brain of patients with Parkinson's disease (PD). A link between α-Syn and mitochondria in …

Resveratrol exerts its neuroprotective effect by modulating mitochondrial dysfunctions and associated cell death during cerebral ischemia

S Yousuf, F Atif, M Ahmad, N Hoda, T Ishrat, B Khan… - Brain research, 2009 - Elsevier
Free radicals are known to cause secondary neuronal damage in cerebral
ischemia/reperfusion (I/R). We investigated here the neuroprotective effect of resveratrol, a …

Mitochondria: a target for neuroprotective interventions in cerebral ischemia-reperfusion

M Christophe, S Nicolas - Current pharmaceutical design, 2006 - ingentaconnect.com
Evidence obtained over the past two decades shows that reactive oxygen species (ROS) are
involved in brain lesions, including those due to cerebral ischemia-reperfusion. The …

Effect of resveratrol on 3-nitropropionic acid-induced biochemical and behavioural changes: possible neuroprotective mechanisms

P Kumar, SSV Padi, PS Naidu… - Behavioural …, 2006 - journals.lww.com
Huntington's disease is a progressive, degenerative disease characterized by abnormal
body movements called chorea, and a reduction of various mental abilities. 3-Nitropropionic …

Mitochondrial DNA modifies cognition in interaction with the nuclear genome and age in mice

PL Roubertoux, F Sluyter, M Carlier, B Marcet… - Nature …, 2003 - nature.com
Several lines of evidence indicate an association between mitochondrial DNA (mtDNA) and
the functioning of the nervous system. As neuronal development, and structure,, as well as …

[HTML][HTML] Antioxidant and neuroprotective actions of resveratrol in cerebrovascular diseases

Q Wang, Q Yu, M Wu - Frontiers in pharmacology, 2022 - frontiersin.org
Cerebralvascular diseases are the most common high-mortality diseases worldwide.
Despite its global prevalence, effective treatments and therapies need to be explored. Given …

Resveratrol, a naturally occurring diphenolic compound, affects lipogenesis, lipolysis and the antilipolytic action of insulin in isolated rat adipocytes

K Szkudelska, L Nogowski, T Szkudelski - The Journal of steroid …, 2009 - Elsevier
Resveratrol is a naturally occurring diphenolic compound exerting numerous beneficial
effects in the organism. The present study demonstrated its short-term, direct influence on …