Ion mobility mass spectrometry (IM-MS) for structural biology: insights gained by measuring mass, charge, and collision cross section

E Christofi, P Barran - Chemical Reviews, 2023 - ACS Publications
The investigation of macromolecular biomolecules with ion mobility mass spectrometry (IM-
MS) techniques has provided substantial insights into the field of structural biology over the …

Ion mobility spectrometry: fundamental concepts, instrumentation, applications, and the road ahead

JN Dodds, ES Baker - Journal of the American Society for Mass …, 2019 - ACS Publications
Ion mobility spectrometry (IMS) is a rapid separation technique that has experienced
exponential growth as a field of study. Interfacing IMS with mass spectrometry (IMS-MS) …

Online parallel accumulation–serial fragmentation (PASEF) with a novel trapped ion mobility mass spectrometer

F Meier, AD Brunner, S Koch, H Koch, M Lubeck… - Molecular & Cellular …, 2018 - ASBMB
In bottom-up proteomics, peptides are separated by liquid chromatography with elution peak
widths in the range of seconds, whereas mass spectra are acquired in about 100 …

Mass spectrometry-based techniques to elucidate the sugar code

M Grabarics, M Lettow, C Kirschbaum, K Greis… - Chemical …, 2021 - ACS Publications
Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins,
and glycans. Although glycans are essential to all living organisms, surprisingly little is …

A cyclic ion mobility-mass spectrometry system

K Giles, J Ujma, J Wildgoose, S Pringle… - Analytical …, 2019 - ACS Publications
Improvements in the performance and availability of commercial instrumentation have made
ion mobility-mass spectrometry (IM-MS) an increasingly popular approach for the structural …

Software tools and approaches for compound identification of LC-MS/MS data in metabolomics

I Blaženović, T Kind, J Ji, O Fiehn - Metabolites, 2018 - mdpi.com
The annotation of small molecules remains a major challenge in untargeted mass
spectrometry-based metabolomics. We here critically discuss structured elucidation …

Recommendations for reporting ion mobility Mass Spectrometry measurements

V Gabelica, AA Shvartsburg, C Afonso… - Mass spectrometry …, 2019 - Wiley Online Library
Here we present a guide to ion mobility mass spectrometry experiments, which covers both
linear and nonlinear methods: what is measured, how the measurements are done, and how …

Guiding the choice of informatics software and tools for lipidomics research applications

Z Ni, M Wölk, G Jukes, K Mendivelso Espinosa… - Nature …, 2023 - nature.com
Progress in mass spectrometry lipidomics has led to a rapid proliferation of studies across
biology and biomedicine. These generate extremely large raw datasets requiring …

Ion mobility mass spectrometry in the omics era: Challenges and opportunities for metabolomics and lipidomics

G Paglia, AJ Smith, G Astarita - Mass Spectrometry Reviews, 2022 - Wiley Online Library
Researchers worldwide are taking advantage of novel, commercially available,
technologies, such as ion mobility mass spectrometry (IM‐MS), for metabolomics and …

Recurrent topics in mass spectrometry-based metabolomics and lipidomics—standardization, coverage, and throughput

E Rampler, YE Abiead, H Schoeny, M Rusz… - Analytical …, 2020 - ACS Publications
We have come a long way in the last years of developing analytical strategies in
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …