[HTML][HTML] MDR/XDR-TB management of patients and contacts: Challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network

GB Migliori, S Tiberi, A Zumla, E Petersen… - International Journal of …, 2020 - Elsevier
The continuous flow of new research articles on MDR-TB diagnosis, treatment, prevention
and rehabilitation requires frequent update of existing guidelines. This review is aimed at …

Genome-based prediction of bacterial antibiotic resistance

M Su, SW Satola, TD Read - Journal of clinical microbiology, 2019 - Am Soc Microbiol
Clinical microbiology has long relied on growing bacteria in culture to determine
antimicrobial susceptibility profiles, but the use of whole-genome sequencing for antibiotic …

[HTML][HTML] The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis

TM Walker, P Miotto, CU Köser, PW Fowler… - The Lancet …, 2022 - thelancet.com
Background Molecular diagnostics are considered the most promising route to achievement
of rapid, universal drug susceptibility testing for Mycobacterium tuberculosis complex …

Treatment of drug-resistant tuberculosis. An official ATS/CDC/ERS/IDSA clinical practice guideline

P Nahid, SR Mase, GB Migliori, G Sotgiu… - American journal of …, 2019 - atsjournals.org
Background: The American Thoracic Society, US Centers for Disease Control and
Prevention, European Respiratory Society, and Infectious Diseases Society of America …

[HTML][HTML] Prediction of susceptibility to first-line tuberculosis drugs by DNA sequencing

CRyPTIC Consortium and the 100,000 … - … England Journal of …, 2018 - Mass Medical Soc
Abstract Background The World Health Organization recommends drug-susceptibility testing
of Mycobacterium tuberculosis complex for all patients with tuberculosis to guide treatment …

Tuberculosis: advances and challenges in development of new diagnostics and biomarkers

G Walzl, R McNerney, N du Plessis, M Bates… - The Lancet Infectious …, 2018 - thelancet.com
Tuberculosis remains the leading cause of death from an infectious disease worldwide.
Early and accurate diagnosis and detection of drug-sensitive and drug-resistant tuberculosis …

[HTML][HTML] A data compendium associating the genomes of 12,289 Mycobacterium tuberculosis isolates with quantitative resistance phenotypes to 13 antibiotics

CRyPTIC Consortium - PLoS biology, 2022 - journals.plos.org
The Comprehensive Resistance Prediction for Tuberculosis: an International Consortium
(CRyPTIC) presents here a data compendium of 12,289 Mycobacterium tuberculosis global …

Management of drug-resistant tuberculosis

C Lange, K Dheda, D Chesov, AM Mandalakas… - The Lancet, 2019 - thelancet.com
Drug-resistant tuberculosis is a major public health concern in many countries. Over the past
decade, the number of patients infected with Mycobacterium tuberculosis resistant to the …

[HTML][HTML] Genome-wide association studies of global Mycobacterium tuberculosis resistance to 13 antimicrobials in 10,228 genomes identify new resistance …

CRyPTIC Consortium - PLoS biology, 2022 - journals.plos.org
The emergence of drug-resistant tuberculosis is a major global public health concern that
threatens the ability to control the disease. Whole-genome sequencing as a tool to rapidly …

Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues

CJ Meehan, GA Goig, TA Kohl, L Verboven… - NATURE reviews …, 2019 - nature.com
Whole genome sequencing (WGS) of Mycobacterium tuberculosis has rapidly progressed
from a research tool to a clinical application for the diagnosis and management of …