[HTML][HTML] CLIP and complementary methods

M Hafner, M Katsantoni, T Köster, J Marks… - Nature Reviews …, 2021 - nature.com
RNA molecules start assembling into ribonucleoprotein (RNP) complexes during
transcription. Dynamic RNP assembly, largely directed by cis-acting elements on the RNA …

[PDF][PDF] The extracellular RNA communication consortium: establishing foundational knowledge and technologies for extracellular RNA research

S Das, AB Abdel-Mageed, C Adamidi, PD Adelson… - Cell, 2019 - cell.com
The Extracellular RNA Communication Consortium (ERCC) was launched to accelerate
progress in the new field of extracellular RNA (exRNA) biology and to establish whether …

[PDF][PDF] exRNA atlas analysis reveals distinct extracellular RNA cargo types and their carriers present across human biofluids

OD Murillo, W Thistlethwaite, J Rozowsky… - Cell, 2019 - cell.com
To develop a map of cell-cell communication mediated by extracellular RNA (exRNA), the
NIH Extracellular RNA Communication Consortium created the exRNA Atlas resource …

Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic …

H Geekiyanage, S Rayatpisheh… - Proceedings of the …, 2020 - National Acad Sciences
MicroRNAs (miRNAs) function cell-intrinsically to regulate gene expression by base-pairing
to complementary mRNA targets while in association with Argonaute, the effector protein of …

The potential of using blood circular RNA as liquid biopsy biomarker for human diseases

G Wen, T Zhou, W Gu - Protein & cell, 2021 - academic.oup.com
Circular RNA (circRNA) is a novel class of single-stranded RNAs with a closed loop
structure. The majority of circRNAs are formed by a back-splicing process in pre-mRNA …

Role of exosomes and exosomal microRNAs in cancer

N Dilsiz - Future science OA, 2020 - Future Science
A growing body of evidence indicates that exosomes play a critical role in the cell–cell
communication process. Exosomes are biological nanoparticles with an average diameter of …

Three-dimensional hierarchical plasmonic nano-architecture based label-free surface-enhanced Raman spectroscopy detection of urinary exosomal miRNA for …

WH Kim, JU Lee, MJ Jeon, KH Park, SJ Sim - Biosensors and Bioelectronics, 2022 - Elsevier
The urinary exosomal miRNAs are recently emerging prostate cancer (PC)-associated
biomarkers for the early-stage diagnosis and prognosis due to their non-invasiveness …

Examining the evidence for extracellular RNA function in mammals

HN Gruner, MT McManus - Nature Reviews Genetics, 2021 - nature.com
The presence of RNAs in the extracellular milieu has sparked the hypothesis that RNA may
play a role in mammalian cell–cell communication. As functional nucleic acids transfer from …

Liquid biopsy: miRNA as a potential biomarker in oral cancer

S Mazumder, S Datta, JG Ray, K Chaudhuri… - Cancer …, 2019 - Elsevier
Oral cancer is one of the leading cancers in South-Asian countries. Despite the easy access
of the oral cavity, the detection and five year survival rates of OSCC patients are dismal …

[HTML][HTML] Current challenges and best practices for cell-free long RNA biomarker discovery

L Cabús, J Lagarde, J Curado, E Lizano… - Biomarker …, 2022 - Springer
The analysis of biomarkers in biological fluids, also known as liquid biopsies, is seen with
great potential to diagnose complex diseases such as cancer with a high sensitivity and …