Role of cytokines as a double-edged sword in sepsis

H Chaudhry, J Zhou, YIN Zhong, MM Ali, F McGuire… - In vivo, 2013 - iv.iiarjournals.org
Background: Sepsis is a deadly immunological disorder and its pathophysiology is still
poorly understood. We aimed to determine if specific pro-inflammatory and anti-inflammatory …

[HTML][HTML] Pathophysiology of the cardio-renal syndromes types 1–5: An uptodate

L Di Lullo, A Bellasi, V Barbera, D Russo, L Russo… - Indian heart …, 2017 - Elsevier
According to the recent definition proposed by the Consensus conference on Acute Dialysis
Quality Initiative Group, the term cardio-renal syndrome (CRS) has been used to define …

Targeting circulating high mobility group box-1 and histones by extracorporeal blood purification as an immunomodulation strategy against critical illnesses

Y Li, Y Chen, T Yang, K Chang, N Deng, W Zhao, B Su - Critical Care, 2023 - Springer
Both high mobility group box-1 (HMGB1) and histones are major damage-associated
molecular patterns (DAPMs) that mediate lethal systemic inflammation, activation of the …

The unrestricted global effort to complete the COOL trial

AW Kirkpatrick, F Coccolini, M Tolonen, S Minor… - World Journal of …, 2023 - Springer
Background Severe complicated intra-abdominal sepsis (SCIAS) has an increasing
incidence with mortality rates over 80% in some settings. Mortality typically results from …

Cardiorenal syndrome

C Ronco, L Di Lullo - Heart failure clinics, 2014 - heartfailure.theclinics.com
The term cardiorenal syndrome (CRS) includes a broad spectrum of diseases within which
both the heart and kidneys are involved, acutely or chronically. According to a recent …

Newly designed CRRT membranes for sepsis and SIRS—a pragmatic approach for bedside intensivists summarizing the more recent advances: a systematic …

PM Honore, R Jacobs, O Joannes-Boyau… - ASAIO …, 2013 - journals.lww.com
In recent years, after all the attention has been focused on the dose for continuous renal
replacement therapy (CRRT) in sepsis and systemic inflammation response syndrome …

Continuous hemodiafiltration with a cytokine-adsorbing hemofilter in patients with septic shock: a preliminary report

H Shiga, H Hirasawa, O Nishida, S Oda… - Blood purification, 2015 - karger.com
Abstract Background/Aim: We investigated the clinical efficacy of continuous
hemodiafiltration (CHDF) with AN69ST hemofilter (AN69ST-CHDF) in patients with septic …

Closed Or Open after Source Control Laparotomy for Severe Complicated Intra-Abdominal Sepsis (the COOL trial): study protocol for a randomized controlled trial

AW Kirkpatrick, F Coccolini, L Ansaloni… - World Journal of …, 2018 - Springer
Background Severe complicated intra-abdominal sepsis (SCIAS) has an increasing
incidence with mortality rates over 80% in some settings. Mortality typically results from …

The urosepsis—a literature review

M Guliciuc, AC Maier, IM Maier, A Kraft, RR Cucuruzac… - Medicina, 2021 - mdpi.com
Urosepsis is a very serious condition with a high mortality rate. The immune response is in
the center of pathophysiology. The therapeutic management of these patients includes …

Cardiorenal syndrome in western countries: epidemiology, diagnosis and management approaches

C Ronco, L Di Lullo - Kidney diseases, 2017 - karger.com
Background: It is well established that a large number of hospitalized patients present
various degrees of heart and kidney dysfunction; primary disease of the heart or kidney often …