Brain Derived Neurotrophic Factor (BDNF) is a key molecule involved in plastic changes
related to learning and memory. The expression of BDNF is highly regulated, and can lead …

Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …

L1CAM is a transmembrane protein expressed on neurons that was presumed to be found
on neuron-derived extracellular vesicles (NDEVs) in human biofluids. We developed a …

When released into biological fluids like blood or saliva, brain extracellular vesicles (EVs)
might provide a window into otherwise inaccessible tissue, contributing useful biomarkers of …

Extracellular vesicles (EVs), including exosomes and (shedding) microvesicles, are
released by nearly all cell types and carry a cargo of proteins and nucleic acids that varies …

Extracellular vesicles (EVs) play an important role in intercellular communication as carriers
of signalling molecules such as bioactive miRNAs, proteins and lipids. EVs are key players …

Background The study of clinically related biological indicators in Major Depression (MD) is
important. The Brain Derived Neurotrophic Factor (BDNF) appears to play an important role …

Skeletal muscle disorders are dramatically increasing with human aging with enormous
sanitary costs and impact on the quality of life. Preventive and therapeutic tools to limit onset …

Movement and regular physical activity are two important factors that help the human body
prevent, reduce and treat different chronic diseases such as obesity, type 2 diabetes, heart …

Bipolar disorder (BD) has been associated with clinical signs of accelerated aging, which
potentially underlies its association with several age-related medical conditions, such as …