[HTML][HTML] Circulating microRNAs as potential biomarkers for psychiatric and neurodegenerative disorders

MMJ Van den Berg, J Krauskopf, JG Ramaekers… - Progress in …, 2020 - Elsevier
Circulating microRNAs (cimiRNAs) are a class of non-encoding RNAs found in bodily fluids
such as blood, cerebrospinal fluid (CSF) and tears. CimiRNAs have been implicated as …

A comprehensive analysis of the role of hnRNP A1 function and dysfunction in the pathogenesis of neurodegenerative disease

JP Clarke, PA Thibault, HE Salapa… - Frontiers in molecular …, 2021 - frontiersin.org
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is a member of the hnRNP family
of conserved proteins that is involved in RNA transcription, pre-mRNA splicing, mRNA …

A blood based 12-miRNA signature of Alzheimer disease patients

P Leidinger, C Backes, S Deutscher, K Schmitt… - Genome biology, 2013 - Springer
Background Alzheimer disease (AD) is the most common form of dementia but the
identification of reliable, early and non-invasive biomarkers remains a major challenge. We …

An overview of the intrinsic role of citrullination in autoimmune disorders

M Alghamdi, D Alasmari, A Assiri… - Journal of …, 2019 - Wiley Online Library
A protein undergoes many types of posttranslation modification. Citrullination is one of these
modifications, where an arginine amino acid is converted to a citrulline amino acid. This …

[HTML][HTML] Profile of 6 microRNA in blood plasma distinguish early stage Alzheimer's disease patients from non-demented subjects

S Nagaraj, K Laskowska-Kaszub, KJ Dębski… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Alzheimers disease (AD) is the most common age-related dementia. Among its major
challenges is identifying molecular signatures characteristic for the early AD stage in …

Imbalance of Circulating Th17 and Regulatory T Cells in Alzheimer's Disease: A Case Control Study

TJ Oberstein, L Taha, P Spitzer, J Hellstern… - Frontiers in …, 2018 - frontiersin.org
The neuropathological hallmarks of Alzheimer's disease (AD), ie, neuritic plaques and
neurofibrillary tangles, consist of beta amyloid peptides (Aβ) and hyperphosphorylated Tau …

Extracellular vesicle as a source of Alzheimer's biomarkers: opportunities and challenges

S Lee, S Mankhong, JH Kang - International journal of molecular sciences, 2019 - mdpi.com
Alzheimer's disease (AD) is a chronic progressive neurodegenerative disease characterized
by memory decline and cognitive dysfunction. Although the primary causes of AD are not …

Linking deregulation of non-coding RNA to the core pathophysiology of Alzheimer's disease: An integrative review

MJ Millan - Progress in neurobiology, 2017 - Elsevier
The human genome encodes a vast repertoire of protein non-coding RNAs (ncRNA), some
specific to the brain. MicroRNAs, which interfere with the translation of target mRNAs, are of …

[HTML][HTML] microRNA diagnostic panel for Alzheimer's disease and epigenetic trade-off between neurodegeneration and cancer

S Nagaraj, KM Zoltowska, K Laskowska-Kaszub… - Ageing research …, 2019 - Elsevier
Abstract microRNAs (miRNAs) have been extensively studied as potential biomarkers for
Alzheimer's disease (AD). Their profiles have been analyzed in blood, cerebrospinal fluid …

Non-coding RNAs in Alzheimer's disease

L Tan, JT Yu, N Hu, L Tan - Molecular neurobiology, 2013 - Springer
Alzheimer's disease (AD) is a complex neurodegenerative disorder and the most common
dementia among the elderly. Accumulating research indicates that noncoding RNAs …