[HTML][HTML] Immunosuppression in lung transplantation

JL Scheffert, K Raza - Journal of thoracic disease, 2014 - ncbi.nlm.nih.gov
Lung transplantation can be a life-saving procedure for those with end-stage lung diseases.
Unfortunately, long term graft and patient survival are limited by both acute and chronic …

Chronic lung allograft rejection: mechanisms and therapy

JA Belperio, SS Weigt, MC Fishbein… - Proceedings of the …, 2009 - atsjournals.org
Lung transplantation is a therapeutic option for patients with end-stage pulmonary disorders.
Unfortunately, due to post–lung transplant complications, both infectious and noninfectious …

Consensus recommendations for use of maintenance immunosuppression in solid organ transplantation: Endorsed by the American College of Clinical Pharmacy …

J Nelson, N Alvey, L Bowman, J Schulte… - … : The Journal of …, 2022 - Wiley Online Library
Advances in maintenance immunosuppression over the past three decades have improved
solid organ transplantation outcomes dramatically. Uninterrupted access to …

Lung microbiota predict chronic rejection in healthy lung transplant recipients: a prospective cohort study

MP Combs, DS Wheeler, JE Luth… - The Lancet …, 2021 - thelancet.com
Background Alterations in the respiratory microbiome are common in chronic lung diseases,
correlate with decreased lung function, and have been associated with disease progression …

The unpleasantness of perceived dyspnea is processed in the anterior insula and amygdala

A von Leupoldt, T Sommer, S Kegat… - American Journal of …, 2008 - atsjournals.org
Rationale: The subjective perception of dyspnea, which is an impairing symptom in various
cardiopulmonary diseases, consists of sensory (intensity) and affective aspects …

Bronchiolitis obliterans syndrome–free survival after lung transplantation: An International Society for Heart and Lung Transplantation Thoracic Transplant Registry …

HS Kulkarni, WS Cherikh, DC Chambers… - The Journal of Heart and …, 2019 - Elsevier
BACKGROUND Lung transplant (LTx) recipients have low long-term survival and a high
incidence of bronchiolitis obliterans syndrome (BOS). However, few long-term, multicenter …

[HTML][HTML] Survival in sensitized lung transplant recipients with perioperative desensitization

KJ Tinckam, S Keshavjee, C Chaparro, D Barth… - American Journal of …, 2015 - Elsevier
Donor-specific HLA antibodies (DSA) have an adverse effect on short-term and long-term
lung transplant outcomes. We implemented a perioperative strategy to treat DSA-positive …

Severity of lymphocytic bronchiolitis predicts long-term outcome after lung transplantation

AR Glanville, CL Aboyoun, A Havryk, M Plit… - American journal of …, 2008 - atsjournals.org
Rationale: Severe and recurrent acute vascular rejection of the pulmonary allograft is an
accepted major risk factor for obliterative bronchiolitis. Objectives: We assessed the role of …

Bronchiolitis obliterans syndrome: the Achilles' heel of lung transplantation

SS Weigt, A DerHovanessian… - … in respiratory and …, 2013 - thieme-connect.com
Lung transplantation is a therapeutic option for patients with end-stage pulmonary disorders.
Unfortunately, chronic lung allograft dysfunction (CLAD), most commonly manifest as …

Tacrolimus and cyclosporine have differential effects on the risk of development of bronchiolitis obliterans syndrome: results of a prospective, randomized international …

H Treede, AR Glanville, W Klepetko, C Aboyoun… - The Journal of heart and …, 2012 - Elsevier
BACKGROUND: Chronic lung allograft dysfunction, which manifests as bronchiolitis
obliterans syndrome (BOS), is recognized as the primary cause of morbidity and mortality …