Maximizing safe resection of low-and high-grade glioma

SL Hervey-Jumper, MS Berger - Journal of neuro-oncology, 2016 - Springer
Surgical resection plays a central role in the management of gliomas. In this study, we
review the evidence in support of extent of resection to improve survival, symptom …

Surgical oncology for gliomas: the state of the art

N Sanai, MS Berger - Nature Reviews Clinical Oncology, 2018 - nature.com
Surgical resection remains the mainstay of treatment for patients with glioma of any grade.
Maximal resection of the tumour is central to achieving long-term disease control; however …

Functional outcome after language mapping for glioma resection

N Sanai, Z Mirzadeh, MS Berger - New England Journal of …, 2008 - Mass Medical Soc
Background Language sites in the cortex of the brain vary among patients. Language
mapping while the patient is awake is an intraoperative technique designed to minimize …

Lessons from brain mapping in surgery for low-grade glioma: insights into associations between tumour and brain plasticity

H Duffau - The Lancet Neurology, 2005 - thelancet.com
Surgical treatment of low-grade gliomas (LGGs) aims to maximise the amount of tumour
tissue resected, while minimising the risk of functional sequelae. In this review I address the …

Association of surgically acquired motor and language deficits on overall survival after resection of glioblastoma multiforme

MJ McGirt, D Mukherjee, KL Chaichana, KD Than… - …, 2009 - journals.lww.com
OBJECTIVE Balancing the benefits of extensive tumor resection with the consequence of
potential postoperative deficits remains a challenge in malignant astrocytoma surgery …

Contribution of intraoperative electrical stimulations in surgery of low grade gliomas: a comparative study between two series without (1985–96) and with (1996–2003) …

H Duffau, M Lopes, F Arthuis, A Bitar… - Journal of Neurology …, 2005 - jnnp.bmj.com
Objectives: Despite the growing use of intraoperative functional mapping in supratentorial
low grade glioma (LGG) surgery, few studies have compared series of patients operated on …

Usefulness of intraoperative electrical subcortical mapping during surgery for low-grade gliomas located within eloquent brain regions: functional results in a …

H Duffau, L Capelle, D Denvil, N Sichez… - Journal of …, 2003 - thejns.org
Object. Although a growing number of authors currently advocate surgery to treat low-grade
gliomas, controversy still persists, especially because of the risk of inducing neurological …

Contrasting acute and slow-growing lesions: a new door to brain plasticity

M Desmurget, F Bonnetblanc, H Duffau - Brain, 2007 - academic.oup.com
The concept of plasticity describes the mechanisms that rearrange cerebral organization
following a brain injury. During the last century, plasticity has been mainly investigated in …

Is preoperative functional magnetic resonance imaging reliable for language areas mapping in brain tumor surgery? Review of language functional magnetic …

C Giussani, FE Roux, J Ojemann, EP Sganzerla… - …, 2010 - journals.lww.com
OBJECTIVE: Language functional magnetic resonance imaging (fMRI) has been used
extensively in the past decade for both clinical and research purposes. Its integration in the …

Functional recovery after surgical resection of low grade gliomas in eloquent brain: hypothesis of brain compensation

H Duffau, L Capelle, D Denvil, N Sichez… - Journal of Neurology …, 2003 - jnnp.bmj.com
Objectives: To describe functional recovery after surgical resection of low grade gliomas
(LGG) in eloquent brain areas, and discuss the mechanisms of compensation. Methods …