Uncovering the mechanisms of virus infection and assembly is crucial for preventing the
spread of viruses and treating viral disease. The technique of single-virus tracking (SVT) …

The study of biomolecules in their native environments is a challenging task because of the
vast complexity of cellular systems. Technologies developed in the last few years for the …

Achieving a spatial resolution that is not limited by the diffraction of light, recent
developments of super-resolution fluorescence microscopy techniques allow the …

Our desire to understand how the individual molecules that make up cells organize, interact,
and communicate to form living systems has led to the burgeoning field of chemical biology …

Dissecting complex cellular processes requires the ability to track biomolecules as they
function within their native habitat. Although genetically encoded tags such as GFP are …

Over the last two decades, nanobodies or single-domain antibodies have found their way in
research, diagnostics, and therapy. These antigen-binding fragments, derived from Camelid …

We report a highly specific, robust and rapid new method for labeling cell surface proteins
with biophysical probes. The method uses the Escherichia coli enzyme biotin ligase (BirA) …

The modification of proteins with synthetic probes is a powerful means of elucidating and
engineering the functions of proteins both in vitro and in live cells or in vivo. Herein we …

Biomoleküle in ihrer natürlichen Umgebung zu erforschen, ist wegen der enormen
Komplexität zellulärer Systeme eine anspruchsvolle Aufgabe. In den letzten Jahren …

A general approach for the sequential labeling of fusion proteins of O6-alkylguanine-DNA
alkyltransferase (AGT) with different fluorophores in mammalian cells is presented. AGT …