G protein-coupled receptors in taste physiology and pharmacology

R Ahmad, JE Dalziel - Frontiers in pharmacology, 2020 - frontiersin.org
Heterotrimeric G protein-coupled receptors (GPCRs) comprise the largest receptor family in
mammals and are responsible for the regulation of most physiological functions. Besides …

Sweeteners and sweetness enhancers

C Belloir, F Neiers, L Briand - … in Clinical Nutrition & Metabolic Care, 2017 - journals.lww.com
Sweeteners and sweetness enhancers : Current Opinion in Clinical Nutrition & Metabolic Care
Sweeteners and sweetness enhancers : Current Opinion in Clinical Nutrition & Metabolic Care …

Comparison of Different Signal Peptides for the Efficient Secretion of the Sweet-Tasting Plant Protein Brazzein in Pichia pastoris

F Neiers, C Belloir, N Poirier, C Naumer, M Krohn… - Life, 2021 - mdpi.com
Brazzein is a small sweet-tasting protein found in the red berries of a West African evergreen
shrub, Pentadiplandra brazzeana Baillon. Brazzein is highly soluble and stable over a large …

Current progress in understanding the structure and function of sweet taste receptor

L Yang, M Cui, B Liu - Journal of Molecular Neuroscience, 2021 - Springer
The sweet taste receptor, which was identified approximately 20 years ago, mediates sweet
taste recognition in humans and other vertebrates. With the development of genomics …

Brazzein and Monellin: Chemical Analysis, Food Industry Applications, Safety and Quality Control, Nutritional Profile and Health Impacts

A Saraiva, C Carrascosa, F Ramos, D Raheem… - Foods, 2023 - mdpi.com
Recently, customers have been keener to buy products manufactured using all-natural
ingredients with positive health properties, but without losing flavor. In this regard, the …

Potential improvement of the thermal stability of sweet-tasting proteins by structural calculations

N Tang, J Liu, Y Cheng - Food chemistry, 2021 - Elsevier
The low thermal stability of the sweet-tasting proteins limited their applications in food
industry. Improve their thermal stability is the key to developing their applications in food …

The novel anti-cancer feature of Brazzein through activating of hTLR5 by integration of biological evaluation: molecular docking and molecular dynamics simulation

M Poursalim, MD Shasaltaneh, V Jafarian… - Scientific Reports, 2022 - nature.com
Many of plant proteins exhibit the properties similar to the antitumor proteins although the
anticancer activity of Brazzein on modulating the autophagy signaling pathway has not been …

A sweeter future: Using protein language models for exploring sweeter brazzein homologs

BN Chua, WM Guo, HT Wong, DSW Ow, PL Ho, W Koh… - Food Chemistry, 2023 - Elsevier
With growing concerns over the health impact of sugar, brazzein offers a viable alternative
due to its sweetness, thermostability, and low risk profile. Here, we demonstrated the ability …

Novel Gurmarin-like Peptides from Gymnema sylvestre and their Interactions with the Sweet Taste Receptor T1R2/T1R3

H Maaroufi - Chemical Senses, 2024 - academic.oup.com
Gymnema sylvestre (GS) is a traditional medicinal plant known for its hypoglycemic and
hypolipidemic effects. Gurmarin (hereafter Gur-1) is the only known active peptide in GS. Gur …

[HTML][HTML] Сладкий белок браззеин как перспективный подсластитель

ЕВ Маркова, ЕИ Леонова, ЮВ Сопова - Вопросы питания, 2024 - cyberleninka.ru
Неумеренное употребление сахаросодержащих продуктов способствует развитию
целого ряда заболеваний, включая ожирение, сахарный диабет и пр. В качестве …