Therapeutic and diagnostic potential of exosomes as drug delivery systems in brain cancer

DI Avgoulas, KS Tasioulis, RM Papi, AA Pantazaki - Pharmaceutics, 2023 - mdpi.com
Cancer is designated as one of the principal causes of mortality universally. Among different
types of cancer, brain cancer remains the most challenging one due to its aggressiveness …

A scientometric analysis and up-to-date review of nano-based drug delivery systems in glioblastoma treatment

Y Xing, F Yasinjan, M Yang, Y Du, H Geng, M He… - Nano Today, 2023 - Elsevier
In recent years, nano-based drug delivery systems have gradually been regarded as a
promising approach to improve the current glioblastoma treatment, attracting many …

[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles in Cancer Therapy Resistance: from Biology to Clinical Opportunity

C Shan, Y Liang, K Wang, P Li - International Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are a type of stromal cells characterized by their properties
of self-renewal and multi-lineage differentiation, which make them prominent in regenerative …

Roles of extracellular vesicles in glioblastoma: foes, friends and informers

TR Lunavat, L Nieland, AB Vrijmoet… - Frontiers in …, 2023 - frontiersin.org
Glioblastoma (GB) tumors are one of the most insidious cancers which take over the brain
and defy therapy. Over time and in response to treatment the tumor and the brain cells in the …

Exosomes in Glioma: Unraveling Their Roles in Progression, Diagnosis, and Therapy

S Yang, Y Sun, W Liu, Y Zhang, G Sun, B Xiang… - Cancers, 2024 - mdpi.com
Simple Summary Glioma is the most prevalent form of primary malignant brain tumor and is
often associated with a grim prognosis. Exosomes, minute extracellular vesicles, are …

[HTML][HTML] Current Non-Metal Nanoparticle-Based Therapeutic Approaches for Glioblastoma Treatment

AM Gawel, A Betkowska, E Gajda, M Godlewska… - Biomedicines, 2024 - mdpi.com
The increase in the variety of nano-based tools offers new possibilities to approach the
therapy of poorly treatable tumors, which includes glioblastoma multiforme (GBM; a primary …

[HTML][HTML] Biology and function of exosomes in tumor immunotherapy

C Liu, C Xia, C Xia - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Exosomes are nano-scale extracellular vesicles that are found widely in various biological
fluids. As messengers, exosomes deliver characteristic biological information from donor …

[HTML][HTML] Exploring emerging concepts of exosomes for the diagnosis, prognosis, and therapeutics of brain cancers

S Banerjee, V Sharma, CD Mukhopadhyay - Extracellular Vesicle, 2024 - Elsevier
Brain cancers, a global menace with high mortality rates, remain a profound challenge,
particularly in treating the most lethal type of malignant tumors like glioblastoma multiforme …

Mesenchymal-Stem-Cell-Based Therapy against Gliomas

SM Santillán-Guaján, MH Shahi, JS Castresana - Cells, 2024 - mdpi.com
Glioblastoma is the most aggressive, malignant, and lethal brain tumor of the central
nervous system. Its poor prognosis lies in its inefficient response to currently available …

Transforming native exosomes to engineered drug vehicles: A smart solution to modern cancer theranostics

RK Sahoo, SK Tripathi, S Biswal, M Panda… - Biotechnology …, 2024 - Wiley Online Library
Exosomes have been the hidden treasure of the cell in terms of cellular interactions,
transportation and therapy. The native exosomes (NEx) secreted by the parent cells hold …