Regulation of mitochondrial ATP production: Ca2+ signaling and quality control

L Boyman, M Karbowski, WJ Lederer - Trends in molecular medicine, 2020 - cell.com
Cardiac ATP production primarily depends on oxidative phosphorylation in mitochondria
and is dynamically regulated by Ca 2+ levels in the mitochondrial matrix as well as by …

Hesperidin: A therapeutic agent for obesity

H Xiong, J Wang, Q Ran, G Lou, C Peng… - Drug design …, 2019 - Taylor & Francis
Obesity is a chronic metabolic disease caused by multiple factors and is considered to be a
risk factor for type 2 diabetes, cardiovascular disease, hypertension, stroke and various …

A narrative review on the role of hesperidin on metabolic parameters, liver enzymes, and inflammatory markers in nonalcoholic fatty liver disease

N Morshedzadeh, A Ramezani Ahmadi… - Food Science & …, 2023 - Wiley Online Library
Insulin resistance, oxidative stress, hyperlipidemia, and inflammation play main roles in the
development of nonalcoholic fatty liver disease (NAFLD). Some studies have reported that …

A comprehensive review of the therapeutic potential of citrus bioflavonoid hesperidin against lifestyle-related disorders

A Ahmad, M Afzaal, F Saeed, SW Ali… - Cogent Food & …, 2023 - Taylor & Francis
The fruits of citrus family are rich in flavonoids with superior antioxidant properties; citrus
bioactive components are potentially beneficial without adverse effects or cytotoxicity in …

Citrus polyphenols and risk of type 2 diabetes: Evidence from mechanistic studies

R Visvanathan, G Williamson - Critical reviews in food science and …, 2023 - Taylor & Francis
Citrus fruits are a rich source of (poly) phenols, a group of dietary bioactive compounds that
protect against developing type 2 diabetes. Our review critically evaluates how experimental …

Calcium influx through the mitochondrial calcium uniporter holocomplex, MCUcx

L Boyman, M Greiser, WJ Lederer - Journal of molecular and cellular …, 2021 - Elsevier
Ca 2+ flux into the mitochondrial matrix through the MCU holocomplex (MCU cx) has
recently been measured quantitatively and with milliseconds resolution for the first time …

Hesperetin is a potent bioactivator that activates SIRT1-AMPK signaling pathway in HepG2 cells

H Shokri Afra, M Zangooei, R Meshkani… - Journal of physiology …, 2019 - Springer
Abstract Sirtuin 1 (SIRT1) is a deacetylase enzyme that plays crucial roles in controlling
many cellular processes and its downregulation has been implicated in different metabolic …

Evidence for toxic advanced glycation end-products generated in the normal rat liver

T Takata, A Sakasai-Sakai, J Takino, M Takeuchi - Nutrients, 2019 - mdpi.com
Glucose/fructose in beverages/foods containing high-fructose corn syrup (HFCS) are
metabolized to glyceraldehyde (GA) in the liver. We previously reported that GA-derived …

Effect of pre-slaughter fasting time on carcass yield, blood parameters and meat quality in broilers

X Wu, Y Zhou, Z Lu, Y Zhang, T Zhang - Animal Bioscience, 2023 - pmc.ncbi.nlm.nih.gov
Objective The aim of this study was to evaluate the effect of pre-slaughter fasting time on
carcass yield, meat quality, blood parameters and glucose metabolism in broilers. Methods …

[HTML][HTML] The metabolic and toxic acute effects of phloretin in the rat liver

FSI Da Silva, PFV Bizerra, MS Mito… - Chemico-Biological …, 2022 - Elsevier
The current study sought to evaluate the acute effects of phloretin (PH) on metabolic
pathways involved in the maintenance of glycemia, specifically gluconeogenesis and …