Biomarkers of methylmercury neurotoxicity and neurodevelopmental features: a systematic review

AC Panzenhagen, F dos Santos Petry… - Food and Chemical …, 2024 - Elsevier
The issue of MeHg contamination is a significant concern due to its detrimental impact on
the environment. This study aimed to thoroughly investigate the effects of MeHg on …

The Beneficial Role of Apigenin against Cognitive and Neurobehavioural Dysfunction: A Systematic Review of Preclinical Investigations

TA Olasehinde, OO Olaokun - Biomedicines, 2024 - mdpi.com
Apigenin is a flavone widely present in different fruits and vegetables and has been
suggested to possess neuroprotective effects against some neurological disorders. In this …

Nrf2/HO-1 signaling stimulation through acetyl-11-keto-beta-boswellic acid (AKBA) provides neuroprotection in ethidium bromide-induced experimental model of …

S Upadhayay, S Mehan, A Prajapati, P Sethi, M Suri… - Genes, 2022 - mdpi.com
Multiple sclerosis (MS) is a severe immune-mediated neurological disease characterized by
neuroinflammation, demyelination, and axonal degeneration in the central nervous system …

Matrine mediated neuroprotective potential in experimental multiple sclerosis: evidence from CSF, blood markers, brain samples and in-silico investigations

S Chhabra, S Mehan, Z Khan, GD Gupta… - Journal of …, 2023 - Elsevier
Multiple sclerosis (MS) is a debilitating, inflammatory, and demyelinating disease of the
central nervous system influenced by environmental and genetic factors. Around 2.8 million …

Acetyl-11-keto-beta boswellic acid (AKBA) modulates CSTC-pathway by activating SIRT-1/Nrf2-HO-1 signalling in experimental rat model of obsessive-compulsive …

P Sethi, S Mehan, Z Khan, S Chhabra - Neurotoxicology, 2023 - Elsevier
Obsessive-Compulsive disorder (OCD) is a long-term and persistent mental illness
characterised by obsessive thoughts and compulsive behaviours. Numerous factors can …

Activation of IGF-1/GLP-1 signalling via 4-hydroxyisoleucine prevents motor neuron impairments in experimental ALS-rats exposed to methylmercury-induced …

A Shandilya, S Mehan, S Kumar, P Sethi, AS Narula… - Molecules, 2022 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a severe adult motor neuron disease that causes
progressive neuromuscular atrophy, muscle wasting, weakness, and depressive-like …

PI3K/AKT/mTOR signalling inhibitor chrysophanol ameliorates neurobehavioural and neurochemical defects in propionic acid-induced experimental model of autism …

A Sharma, S Bhalla, S Mehan - Metabolic brain disease, 2022 - Springer
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder marked by
social and communication deficits as well as repetitive behaviour. Several studies have …

Effect of natural adenylcyclase/cAMP/CREB signalling activator forskolin against intra-striatal 6-OHDA-lesioned Parkinson's rats: preventing mitochondrial, motor and …

M Alharbi, A Alshammari, G Kaur, S Kalra, S Mehan… - Molecules, 2022 - mdpi.com
Parkinson's disease (PD) is characterised by dopaminergic neuronal loss in the brain area.
PD is a complex disease that deteriorates patients' motor and non-motor functions. In …

Physiochemical, biological, and therapeutic uses of stingless bee honey

AS Gadge, DV Shirsat, PS Soumia, CL Pote… - … in Sustainable Food …, 2024 - frontiersin.org
Stingless bee honey, also known as pot honey, is a unique product that differs from other
honey (Apis) in terms of flavor, chemical composition, biological characteristics, and …

[HTML][HTML] Effect of alpha-mangostin in the prevention of behavioural and neurochemical defects in methylmercury-induced neurotoxicity in experimental rats

R Sahu, S Mehan, S Kumar, A Prajapati, A Alshammari… - Toxicology reports, 2022 - Elsevier
Methylmercury (MeHg+) is a known neurotoxin that causes progressive motor neuron
degeneration in the central nervous system. Axonal degeneration, oligodendrocyte …