Patients with suppressed immunity are at the highest risk for hospital-acquired infections.
Among these, invasive candidiasis is the most prevalent systemic fungal nosocomial …

Telomerase is a eukaryotic ribonucleoprotein (RNP) whose specialized reverse
transcriptase action performs de novo synthesis of one strand of telomeric DNA. The …

Telomerase is a special reverse transcriptase ribonucleoprotein dedicated to the synthesis
of telomere repeats that protect chromosome ends. Among reverse transcriptases …

The non-coding RNA subunit of telomerase provides the template for telomerase activity. In
diverse fungi, 3′ end processing of telomerase RNA involves a single cleavage by the …

Telomerase is a unique reverse transcriptase that catalyzes the addition of telomere DNA
repeats onto the 3′ ends of linear chromosomes and plays a critical role in maintaining …

To elucidate the molecular nature of evolutionary changes of telomeres in the plant order
Asparagales, we aimed to characterize telomerase RNA subunits (TRs) in these plants. The …

Telomerase adds simple-sequence repeats to the ends of linear chromosomes to counteract
the loss of end sequence inherent in conventional DNA replication. Catalytic activity for …

Telomerase is the eukaryotic solution to the 'end-replication problem'of linear chromosomes
by synthesising the highly repetitive DNA constituent of telomeres, the nucleoprotein cap …

The enormous sequence heterogeneity of telomerase RNA (TR) subunits has thus far
complicated their characterization in a wider phylogenetic range. Our recent finding that land …

The vast body of literature regarding human telomere maintenance is a true testament to the
importance of understanding telomere regulation in both normal and diseased states. In this …