Peripheral inflammation, defined as inflammation that occurs outside the central nervous
system, is an age-related phenomenon that has been identified as a risk factor for …

Background Systemic inflammation has been suggested to be associated with Alzheimer's-
disease progression, although whether it is a cause or a downstream effect is still …

Background There is considerable evidence suggesting a role of neuroinflammation in the
pathogenesis of Alzheimer's disease. Establishing causality is challenging due to bias from …

Numerous studies have reported that circulating cytokines (CCs) are linked to age-related
neurodegenerative diseases (ANDDs); however, there is a lack of systematic investigation …

The aim of this study was to explore the association between genetically predicted
circulating levels of immunity and inflammation, and the risk of Alzheimer's disease (AD) and …

Background: The etiology of dementia may partly be underpinned by impaired lung function
via systemic inflammation and hypoxia. Objective: To prospectively examine the association …

Objective Growing evidence suggests that patients with rheumatoid arthritis (RA) have
increased risk for dementia. We assessed risk factors for incident dementia in an inception …

To find drivers of healthy ageing, a genome-wide association study (GWAS) was performed
in healthy and unhealthy older individuals. Healthy individuals were defined as free from …

Objective. Growing evidence suggests that patients with rheumatoid arthritis (RA) have
increased risk for dementia. We assessed risk factors for incident dementia in an inception …

Background: The etiology of dementia may partly be underpinned by impaired lung function
via systemic inflammation and hypoxia. Objective: To prospectively examine the association …