Anti‐Schistosoma mansoni effects of essential oils and their components

MT Islam, M Martorell, B Salehi, WN Setzer… - Phytotherapy …, 2020 - Wiley Online Library
Schistosoma mansoni is endemic in 55 countries around the world. S. mansoni is a water‐
borne parasite of humans belonging to the group of blood flukes. Generally, schistosomiasis …

The Clinical Translation of α-humulene–A Scoping Review

N Dalavaye, M Nicholas, M Pillai, S Erridge… - Planta …, 2024 - thieme-connect.com
α-humulene, a sesquiterpene found in essential oils of various plant species, has garnered
interest due to its potential therapeutic applications. This scoping review aims to consolidate …

[HTML][HTML] An Abies procera-derived tetracyclic triterpene containing a steroid-like nucleus core and a lactone side chain attenuates in vitro survival of both Fasciola …

HL Whiteland, A Chakroborty, JE Forde-Thomas… - International Journal for …, 2018 - Elsevier
Two economically and biomedically important platyhelminth species, Fasciola hepatica
(liver fluke) and Schistosoma mansoni (blood fluke), are responsible for the neglected …

In vitro and in vivo evaluation of six artemisinin derivatives against Schistosoma mansoni

SAP Corrêa, RN de Oliveira, TMF Mendes… - Parasitology …, 2019 - Springer
Schistosomiasis is a tropical neglected disease whose socioeconomic impact is surpassed
only by malaria. Until recently, praziquantel (PZQ) has been the only available drug, raising …

Licochalcone A induces morphological and biochemical alterations in Schistosoma mansoni adult worms

RL Souza, UO Gonçalves, FR Badoco… - Biomedicine & …, 2017 - Elsevier
This paper is the first report on the in vitro effects of licochalcone A, a chalcone isolated from
Glycyrrhiza inflate Batalin (Leguminosae), on Schistosoma mansoni adult worms. In vitro …

Synthetic Aurones: New Features for Schistosoma mansoni Therapy

D Silva Torres, B Alves de Oliveira… - Chemistry & …, 2021 - Wiley Online Library
In this work, two synthetic aurones revealed moderate schistosomicidal potential in in vitro
and in vivo assays. Aurones (1) and (2) promoted changes in tegument integrity and motor …

[HTML][HTML] In vitro and in silico evaluation of the schistosomicidal activity of eugenol derivatives using biochemical, molecular, and morphological tools

IMM Souza, RD Novaes, RV Gonçalves… - Journal of Venomous …, 2022 - SciELO Brasil
Background Eugenol shows both antibacterial and antiparasitic activities, suggesting that it
might be evaluated as an option for the treatment of praziquantel-resistant schistosome …

The promising antischistosomal activity of oleic acid-loaded polymeric nanocapsules for oral administration

RN de Oliveira, PM Campos, RMC Pinto… - Journal of Drug Delivery …, 2021 - Elsevier
Abstract Neglected Tropical Diseases, such as schistosomiasis, still affect thousands of
people, presenting high morbidity rates. Currently, praziquantel is the only drug available for …

In vitro schistosomicidal activity of tamoxifen and its effectiveness in a murine model of schistosomiasis at a single dose

RN Oliveira, SAP Corrêa, KM Vieira, T Mendes… - Parasitology …, 2019 - Springer
Schistosomiasis is a neglected tropical disease affecting 220 million people worldwide.
Praziquantel has proven to be effective against this parasitic disease, though there are …

[HTML][HTML] The effect of Spondias mombin L. against Strongyloides venezuelensis: An in vitro approach

PB da Silva Medeiros, TMF Mendes, VL Garcia… - Acta Tropica, 2022 - Elsevier
Strongyloidiasis is a neglected tropical disease mainly caused by the nematode parasite
Strongyloides stercoralis. Current treatment consists in the administration of ivermectin or …