Neurogenesis in aging and age-related neurodegenerative diseases

L Culig, X Chu, VA Bohr - Ageing research reviews, 2022 - Elsevier
Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …

[HTML][HTML] Appropriate exercise level attenuates gut dysbiosis and valeric acid increase to improve neuroplasticity and cognitive function after surgery in mice

Z Lai, W Shan, J Li, J Min, X Zeng, Z Zuo - Molecular psychiatry, 2021 - nature.com
Postoperative cognitive dysfunction (POCD) affects the outcome of millions of patients each
year. Aging is a risk factor for POCD. Here, we showed that surgery induced learning and …

[HTML][HTML] Current understanding of the roles of gut–brain Axis in the cognitive deficits caused by perinatal stress exposure

MR Rubinstein, AL Burgueño, S Quiroga, MR Wald… - Cells, 2023 - mdpi.com
The term 'perinatal environment'refers to the period surrounding birth, which plays a crucial
role in brain development. It has been suggested that dynamic communication between the …

Environmental enrichment alters neurobehavioral development following maternal immune activation in mice offspring with epilepsy

M Zeraati, N Najdi, B Mosaferi, AA Salari - Behavioural brain research, 2021 - Elsevier
Epilepsy is a chronic brain disease affecting millions of people worldwide. Anxiety-related
disorders and cognitive deficits are common in patients with epilepsy. Previous studies have …

[HTML][HTML] Restoring age-related cognitive decline through environmental enrichment: A transcriptomic approach

S Schmidt, M Haase, L Best, M Groth, J Lindner… - Cells, 2022 - mdpi.com
Cognitive decline is one of the greatest health threats of old age and the maintenance of
optimal brain function across a lifespan remains a big challenge. The hippocampus is …

Long‐term environmental enrichment relieves dysfunctional cognition and synaptic protein levels induced by prenatal inflammation in older CD‐1 mice

ZZ Zhang, LP Zeng, J Chen, YF Wu, YT Wang… - Neural …, 2022 - Wiley Online Library
A mounting body of evidence suggests that prenatal inflammation may enhance the rate of
age‐associated cognitive decline and may involve aberrant amounts of synaptic proteins in …

Environmental enrichment: dissociated effects between physical activity and changing environmental complexity on anxiety and neurogenesis in adult male Balb/C …

GB Ramírez-Rodríguez, B Gutiérrez-Vera… - Physiology & …, 2022 - Elsevier
Several factors, including environmental modifications, stimulate neuroplasticity. One type of
neuroplasticity consists in the generation of new neurons in the dentate gyrus of the …

Naturalistic versus unnaturalistic environments

C Warwick, C Steedman - Health and welfare of captive reptiles, 2023 - Springer
Reptiles are kept in diverse husbandry situations, including zoological collections, private
pet or hobby keeping, scientific and laboratory studies, quarantine, and numerous …

Chronic running‐wheel exercise from adolescence leads to increased anxiety and depression‐like phenotypes in adulthood in rats: Effects on stress markers and …

EJ Jaehne, JN Kent, N Lam, L Schonfeld… - Developmental …, 2023 - Wiley Online Library
Exercise has been shown to be beneficial in reducing symptoms of affective disorders and to
increase the expression of brain‐derived neurotrophic factor (BDNF). The BDNF Val66Met …

[HTML][HTML] Mindfulness intervention improves cognitive function in older adults by enhancing the level of miRNA-29c in neuron-derived extracellular vesicles

S Hashizume, M Nakano, K Kubota, S Sato… - Scientific Reports, 2021 - nature.com
Although mindfulness-based stress reduction (MBSR) improves cognitive function, the
mechanism is not clear. In this study, people aged 65 years and older were recruited from …