Neurogenesis in aging and age-related neurodegenerative diseases
Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …
adult brain, declines in an age-dependent manner and is one potential target for extending …
[HTML][HTML] Appropriate exercise level attenuates gut dysbiosis and valeric acid increase to improve neuroplasticity and cognitive function after surgery in mice
Postoperative cognitive dysfunction (POCD) affects the outcome of millions of patients each
year. Aging is a risk factor for POCD. Here, we showed that surgery induced learning and …
year. Aging is a risk factor for POCD. Here, we showed that surgery induced learning and …
[HTML][HTML] Current understanding of the roles of gut–brain Axis in the cognitive deficits caused by perinatal stress exposure
The term 'perinatal environment'refers to the period surrounding birth, which plays a crucial
role in brain development. It has been suggested that dynamic communication between the …
role in brain development. It has been suggested that dynamic communication between the …
Environmental enrichment alters neurobehavioral development following maternal immune activation in mice offspring with epilepsy
Epilepsy is a chronic brain disease affecting millions of people worldwide. Anxiety-related
disorders and cognitive deficits are common in patients with epilepsy. Previous studies have …
disorders and cognitive deficits are common in patients with epilepsy. Previous studies have …
[HTML][HTML] Restoring age-related cognitive decline through environmental enrichment: A transcriptomic approach
S Schmidt, M Haase, L Best, M Groth, J Lindner… - Cells, 2022 - mdpi.com
Cognitive decline is one of the greatest health threats of old age and the maintenance of
optimal brain function across a lifespan remains a big challenge. The hippocampus is …
optimal brain function across a lifespan remains a big challenge. The hippocampus is …
Long‐term environmental enrichment relieves dysfunctional cognition and synaptic protein levels induced by prenatal inflammation in older CD‐1 mice
ZZ Zhang, LP Zeng, J Chen, YF Wu, YT Wang… - Neural …, 2022 - Wiley Online Library
A mounting body of evidence suggests that prenatal inflammation may enhance the rate of
age‐associated cognitive decline and may involve aberrant amounts of synaptic proteins in …
age‐associated cognitive decline and may involve aberrant amounts of synaptic proteins in …
Environmental enrichment: dissociated effects between physical activity and changing environmental complexity on anxiety and neurogenesis in adult male Balb/C …
GB Ramírez-Rodríguez, B Gutiérrez-Vera… - Physiology & …, 2022 - Elsevier
Several factors, including environmental modifications, stimulate neuroplasticity. One type of
neuroplasticity consists in the generation of new neurons in the dentate gyrus of the …
neuroplasticity consists in the generation of new neurons in the dentate gyrus of the …
Naturalistic versus unnaturalistic environments
C Warwick, C Steedman - Health and welfare of captive reptiles, 2023 - Springer
Reptiles are kept in diverse husbandry situations, including zoological collections, private
pet or hobby keeping, scientific and laboratory studies, quarantine, and numerous …
pet or hobby keeping, scientific and laboratory studies, quarantine, and numerous …
Chronic running‐wheel exercise from adolescence leads to increased anxiety and depression‐like phenotypes in adulthood in rats: Effects on stress markers and …
EJ Jaehne, JN Kent, N Lam, L Schonfeld… - Developmental …, 2023 - Wiley Online Library
Exercise has been shown to be beneficial in reducing symptoms of affective disorders and to
increase the expression of brain‐derived neurotrophic factor (BDNF). The BDNF Val66Met …
increase the expression of brain‐derived neurotrophic factor (BDNF). The BDNF Val66Met …
[HTML][HTML] Mindfulness intervention improves cognitive function in older adults by enhancing the level of miRNA-29c in neuron-derived extracellular vesicles
S Hashizume, M Nakano, K Kubota, S Sato… - Scientific Reports, 2021 - nature.com
Although mindfulness-based stress reduction (MBSR) improves cognitive function, the
mechanism is not clear. In this study, people aged 65 years and older were recruited from …
mechanism is not clear. In this study, people aged 65 years and older were recruited from …