Cells typically respond quickly to stress, altering their metabolism to compensate. In
mammalian cells, stress signaling usually leads to either cell-cycle arrest or apoptosis …

This work reviews nuclear compartments, defined broadly to include distinct nuclear
structures, bodies, and chromosome domains. It first summarizes original cytological …

Nuclear speckles, also known as interchromatin granule clusters, are nuclear domains
enriched in pre-mRNA splicing factors, located in the interchromatin regions of the …

Though creation and characterization of water soluble luminescent silver nanodots were
achieved only in the past decade, a large variety of emitters in diverse scaffolds have been …

Higher eukaryotic cell nuclei are highly compartmentalized into bodies and structural
assemblies of specialized functions. Nuclear speckles/IGCs are one of the most prominent …

Phase-separated membraneless bodies play important roles in nucleic acid biology. While
current models for the roles of phase separation largely focus on the compartmentalization …

The Cajal body (CB) is a nuclear organelle present in all eukaryotes that have been
carefully studied. It is identified by the signature protein coilin and by CB-specific RNAs …

During the second half of the 20th century, the introduction of a variety of new techniques
greatly expanded our knowledge of the structure of nerve and neuroglial cells and of the …

It has long been proposed that nuclear RNAs might play an important role in organizing the
structure of the nucleus. Initial experiments performed more than 30 years ago found that …

Advancing our understanding of neuroplasticity and the development of novel therapeutics
based upon this knowledge is critical in order to improve the treatment and prevention of a …