Mechanisms of disease: pemphigus and bullous pemphigoid

CM Hammers, JR Stanley - Annual Review of Pathology …, 2016 - annualreviews.org
Pemphigus and bullous pemphigoid are autoantibody-mediated blistering skin diseases. In
pemphigus, keratinocytes in epidermis and mucous membranes lose cell-cell adhesion, and …

Bullous pemphigoid: a review of its diagnosis, associations and treatment

P Bernard, F Antonicelli - American journal of clinical dermatology, 2017 - Springer
Bullous pemphigoid (BP) is the most common autoimmune subepidermal blistering disease
in Western countries, and typically affects the elderly. BP is immunologically characterized …

[HTML][HTML] Diagnosis of autoimmune blistering diseases

M Witte, D Zillikens, E Schmidt - Frontiers in medicine, 2018 - frontiersin.org
Autoimmune skin blistering diseases (AIBD) are characterized by autoantibodies that are
directed against structural proteins in the skin and adjacent mucous membranes. Some …

Serum levels of autoantibodies to BP180 correlate with disease activity in patients with bullous pemphigoid

E Schmidt, K Obe, EB Bröcker… - Archives of …, 2000 - jamanetwork.com
Objective To investigate the possible correlation of levels of circulating anti-BP180
autoantibodies with disease activity in bullous pemphigoid (BP). Design Diagnostic study …

S2k guideline for the diagnosis of pemphigus vulgaris/foliaceus and bullous pemphigoid

E Schmidt, M Goebeler, M Hertl… - … = Journal of the …, 2015 - pubmed.ncbi.nlm.nih.gov
S2k guideline for the diagnosis of pemphigus vulgaris/foliaceus and bullous pemphigoid S2k
guideline for the diagnosis of pemphigus vulgaris/foliaceus and bullous pemphigoid J Dtsch …

Humanization of autoantigen

W Nishie, D Sawamura, M Goto, K Ito, A Shibaki… - Nature medicine, 2007 - nature.com
Transmissibility of characteristic lesions to experimental animals may help us understand
the pathomechanism of human autoimmune disease. Here we show that human …

Correlation of serum levels of IgE autoantibodies against BP180 with bullous pemphigoid disease activity

N Van Beek, N Lüttmann, F Huebner, A Recke… - JAMA …, 2017 - jamanetwork.com
Importance Bullous pemphigoid (BP) is by far the most frequent autoimmune blistering
disease. The presence of IgE autoantibodies against the transmembrane protein BP antigen …

Modern diagnosis of autoimmune blistering skin diseases

E Schmidt, D Zillikens - Autoimmunity reviews, 2010 - Elsevier
The diagnostic gold standard of autoimmune bullous diseases is the detection of
autoantibodies in skin or mucous membranes by direct immunofluorescence microscopy of …

Immunopathology and molecular diagnosis of autoimmune bullous diseases

S Mihai, C Sitaru - Journal of cellular and molecular medicine, 2007 - Wiley Online Library
• Introduction• Pemphigus diseases‐Pemphigus vulgaris‐Pemphigus foliaceus• Pemphigus
variants‐Pemphigus herpetiformis‐Pemphigus erythematosus‐Drug‐induced pemphigus …

[HTML][HTML] Induction of dermal-epidermal separation in mice by passive transfer of antibodies specific to type VII collagen

C Sitaru, S Mihai, C Otto, MT Chiriac… - The Journal of …, 2005 - Am Soc Clin Investig
Epidermolysis bullosa acquisita (EBA) is a subepidermal blistering disorder associated with
tissue-bound and circulating autoantibodies specific to type VII collagen, a major constituent …