[HTML][HTML] Enhancing the therapeutic efficacy of nanoparticles for cancer treatment using versatile targeted strategies

H Tian, T Zhang, S Qin, Z Huang, L Zhou, J Shi… - Journal of hematology & …, 2022 - Springer
Poor targeting of therapeutics leading to severe adverse effects on normal tissues is
considered one of the obstacles in cancer therapy. To help overcome this, nanoscale drug …

[HTML][HTML] UK Biobank: a globally important resource for cancer research

MC Conroy, B Lacey, J Bešević, W Omiyale… - British Journal of …, 2023 - nature.com
UK Biobank is a large-scale prospective study with deep phenotyping and genomic data. Its
open-access policy allows researchers worldwide, from academia or industry, to perform …

[HTML][HTML] Machine learning: a new prospect in multi-omics data analysis of cancer

B Arjmand, SK Hamidpour, A Tayanloo-Beik… - Frontiers in …, 2022 - frontiersin.org
Cancer is defined as a large group of diseases that is associated with abnormal cell growth,
uncontrollable cell division, and may tend to impinge on other tissues of the body by different …

Omics approaches for the assessment of biological responses to nanoparticles

Y Abdelkader, L Perez-Davalos, R LeDuc… - Advanced Drug Delivery …, 2023 - Elsevier
Nanotechnology has enabled the development of innovative therapeutics, diagnostics, and
drug delivery systems. Nanoparticles (NPs) can influence gene expression, protein …

[HTML][HTML] Identification and characterization of post-translational modifications: Clinical implications

J Hermann, L Schurgers, V Jankowski - Molecular aspects of medicine, 2022 - Elsevier
Post-translational modifications (PTMs) generate marginally modified isoforms of native
peptides, proteins and lipoproteins thereby regulating protein functions, molecular …

Artificial intelligence (AI) and machine learning (ML) in precision oncology: a review on enhancing discoverability through multiomics integration

L Wei, D Niraula, EDH Gates, J Fu, Y Luo… - The British Journal of …, 2023 - academic.oup.com
Multiomics data including imaging radiomics and various types of molecular biomarkers
have been increasingly investigated for better diagnosis and therapy in the era of precision …

[HTML][HTML] Biomedical applications of MnO2 nanomaterials as nanozyme-based theranostics

S Sisakhtnezhad, M Rahimi, S Mohammadi - Biomedicine & …, 2023 - Elsevier
Abstract Manganese dioxide (MnO 2) nanoenzymes/nanozymes (MnO 2-NEs) are 1–100
nm nanomaterials that mimic catalytic, oxidative, peroxidase, and superoxide dismutase …

[HTML][HTML] Multi-omics integration for the design of novel therapies and the identification of novel biomarkers

T Ivanisevic, RN Sewduth - Proteomes, 2023 - mdpi.com
Multi-omics is a cutting-edge approach that combines data from different biomolecular
levels, such as DNA, RNA, proteins, metabolites, and epigenetic marks, to obtain a holistic …

[HTML][HTML] The future of precision oncology

SL Rulten, RP Grose, SA Gatz, JL Jones… - International Journal of …, 2023 - mdpi.com
Our understanding of the molecular mechanisms underlying cancer development and
evolution have evolved rapidly over recent years, and the variation from one patient to …

[HTML][HTML] Mass spectrometry-based proteomics as an emerging tool in clinical laboratories

AG Birhanu - Clinical Proteomics, 2023 - Springer
Mass spectrometry (MS)-based proteomics have been increasingly implemented in various
disciplines of laboratory medicine to identify and quantify biomolecules in a variety of …