Inflammation appears to be a necessity for both metastasis and elimination of tumor cells. IL-
17, a proinflammatory cytokine produced by Th17 cells, contributes to both the processes by …

Breast cancer is the most common malignancy in the female population with a high mortality
rate. Despite the satisfying depth of studies evaluating the contributory role of immune …

Microbial biochemicals have been indicated as the primary stimulators of innate immunity,
the first line of the body's defence against infections. However, the influence of topological …

Background Berberine is a plant-derived alkaloid with potent anti-cancer activities.
Berberine may redirect the tumor-promoting immunosuppressive M2 macrophages, to …

Targeting immunotherapeutics inside the tumor microenvironment (TME) with intact
biological activity remains a pressing issue. Mycobacterium indicus pranii (MIP), an …

Due to its slow progression and susceptibility to radical forms of treatment, low-grade PC is
associated with high overall survival (OS). With the clinical progression of PC, the therapy is …

Treatment with immune complexes, which ligate Fcγ receptors (FcγRs), suppresses the
development of experimental autoimmune encephalomyelitis (EAE). To determine the …

A large amount of information is available, in the medical literature, on the molecular and
immunological mechanisms in which T‐and B‐cells are involved in the pathogenesis of …

Dendritic cell (DC)-expressed CD40 is shown to play crucial roles in eliciting effector T cell
responses, primarily the proinflammatory CD4+ Th subsets and cytotoxic CD8+ T cells that …

Head and neck squamous cell carcinomas (HNSCCs) are closely linked with
immunosuppression, accompanied by complex immune cell functional activities. The …