Short chain fatty acids: microbial metabolites for gut-brain axis signalling

KJ O'Riordan, MK Collins, GM Moloney… - Molecular and Cellular …, 2022 - Elsevier
The role of the intestinal microbiota as a regulator of gut-brain axis signalling has risen to
prominence in recent years. Understanding the relationship between the gut microbiota, the …

The effect of probiotics on the production of short-chain fatty acids by human intestinal microbiome

P Markowiak-Kopeć, K Śliżewska - Nutrients, 2020 - mdpi.com
The relationship between diet and the diversity and function of the intestinal microbiome and
its importance for human health is currently the subject of many studies. The type and …

Beneficial effects on host energy metabolism of short-chain fatty acids and vitamins produced by commensal and probiotic bacteria

JG LeBlanc, F Chain, R Martín… - Microbial cell …, 2017 - Springer
The aim of this review is to summarize the effect in host energy metabolism of the production
of B group vitamins and short chain fatty acids (SCFA) by commensal, food-grade and …

[HTML][HTML] Promotion of astrocyte-neuron glutamate-glutamine shuttle by SCFA contributes to the alleviation of Alzheimer's disease

Y Sun, H Zhang, X Zhang, W Wang, Y Chen, Z Cai… - Redox Biology, 2023 - Elsevier
The brain is particularly susceptible to oxidative damage which is a key feature of several
neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD) …

Butyrate: implications for intestinal function

AJ Leonel, JI Alvarez-Leite - Current Opinion in Clinical Nutrition & …, 2012 - journals.lww.com
From studies published over 30 years, there is no doubt of the important role that butyrate
plays in maintaining intestinal homeostasis. However, despite these effects, clinical studies …

The interplay of dietary fibers and intestinal microbiota affects type 2 diabetes by generating short-chain fatty acids

M Mazhar, Y Zhu, L Qin - Foods, 2023 - mdpi.com
Foods contain dietary fibers which can be classified into soluble and insoluble forms. The
nutritional composition of fast foods is considered unhealthy because it negatively affects the …

A review of the potential mechanisms for the lowering of colorectal oncogenesis by butyrate

KYC Fung, L Cosgrove, T Lockett, R Head… - British Journal of …, 2012 - cambridge.org
Colorectal cancer (CRC) is a leading cause of preventable cancer deaths worldwide, with
dietary factors being recognised as key risk modifiers. Foods containing dietary fibre are …

Lacticaseibacillus rhamnosus Fmb14 prevents purine induced hyperuricemia and alleviate renal fibrosis through gut-kidney axis

H Zhao, X Chen, L Zhang, F Meng, L Zhou… - Pharmacological …, 2022 - Elsevier
Hyperuricemia is a critical threat to human health, and conventional medical treatment only
aims to treat acute gouty arthritis. Purine diet-mediated chronic hyperuricemia and related …

The emerging role of microbiota-derived short-chain fatty acids in immunometabolism

SA Jasim, MJC Opulencia, AA Ramírez-Coronel… - International …, 2022 - Elsevier
The accumulating evidence revealed that microbiota plays a significant function in training,
function, and the induction of host immunity. Once this interaction (immune system …

Butyrate and colorectal cancer: the role of butyrate transport

P Gonçalves, F Martel - Current drug metabolism, 2013 - ingentaconnect.com
Colorectal cancer (CRC) is one of the most common solid tumors worldwide. A diet rich in
dietary fiber is associated with a reduction in its risk. Butyrate (BT) is one of the main end …