Mycobacteria are endowed with mechanisms through which they can evade the onslaught
of host defense response. These mechanisms are discussed including diminishing the …

Serological antibody detection tests for tuberculosis may offer the potential to improve
diagnosis. Recent meta-analyses have shown that commercially available tests have …

A Phase I interventional Clinical Trial was performed with a potential tuberculosis vaccine,
based on detoxified cellular fragments of M. tuberculosis, named RUTI®. The objective was …

One‐third of the world population is estimated to have Mycobacterium tuberculosis infection.
Accurate and timely identification of infected individuals is critical for treatment and control …

Hypoxia and low concentrations of nitric oxide have been reported to upregulate in vitro
gene expression of 48 proteins of the dormancy (DosR) regulon of Mycobacterium …

Tuberculosis continues to be a major health problem worldwide, affecting millions of people
each year. Accurate and rapid diagnosis is key to controlling the disease, yet the traditional …

Sarcoidosis (SA) is a granulomatous disorder of an unknown etiology. Infectious, genetic
factors and autoimmunity have been explored as potential causes of SA. Pathologic …

We demonstrated that not whole Mycobacterium tuberculosis but its particular antigens,
hsp70 Mtb, hsp65 Mtb, and hsp16 Mtb, are present in lymph node tissues of patients with …

Detection of specific antibodies may represent an additional tool in diagnosis of tuberculosis
(TB). Herein, levels of serum IgG antibodies against early secreted antigenic target (ESAT …

Abstract Acid Fast Bacilli (AFB) microscopy smear remains the most widely used laboratory
diagnostic technique for Pulmonary Tuberculosis (PTB) in low-and-middle income countries …