Astrocytes in human central nervous system diseases: a frontier for new therapies
A Verkhratsky, A Butt, B Li, P Illes, R Zorec… - … and Targeted Therapy, 2023 - nature.com
Astroglia are a broad class of neural parenchymal cells primarily dedicated to homoeostasis
and defence of the central nervous system (CNS). Astroglia contribute to the …
and defence of the central nervous system (CNS). Astroglia contribute to the …
The emerging nature of astrocyte diversity
BS Khakh, B Deneen - Annual review of neuroscience, 2019 - annualreviews.org
Astrocytes are morphologically complex, ubiquitous cells that are viewed as a
homogeneous population tiling the entire central nervous system (CNS). However, this view …
homogeneous population tiling the entire central nervous system (CNS). However, this view …
Calcium signaling in astrocytes and gliotransmitter release
Glia are as numerous in the brain as neurons and widely known to serve supportive roles
such as structural scaffolding, extracellular ionic and neurotransmitter homeostasis, and …
such as structural scaffolding, extracellular ionic and neurotransmitter homeostasis, and …
Implication of cerebral astrocytes in major depression: a review of fine neuroanatomical evidence in humans
LA O'Leary, N Mechawar - Glia, 2021 - Wiley Online Library
Postmortem investigations have implicated astrocytes in many neurological and psychiatric
conditions. Multiple brain regions from individuals with major depressive disorder (MDD) …
conditions. Multiple brain regions from individuals with major depressive disorder (MDD) …
Human-specific ARHGAP11B induces hallmarks of neocortical expansion in developing ferret neocortex
The evolutionary increase in size and complexity of the primate neocortex is thought to
underlie the higher cognitive abilities of humans. ARHGAP11B is a human-specific gene …
underlie the higher cognitive abilities of humans. ARHGAP11B is a human-specific gene …
Multicolor multiscale brain imaging with chromatic multiphoton serial microscopy
Large-scale microscopy approaches are transforming brain imaging, but currently lack
efficient multicolor contrast modalities. We introduce chromatic multiphoton serial (ChroMS) …
efficient multicolor contrast modalities. We introduce chromatic multiphoton serial (ChroMS) …
Digital reconstruction of the neuro-glia-vascular architecture
Astrocytes connect the vasculature to neurons mediating the supply of nutrients and
biochemicals. They are involved in a growing number of physiological and …
biochemicals. They are involved in a growing number of physiological and …
Anatomy and spatial organization of Müller glia in mouse retina
Müller glia, the most abundant glia of vertebrate retina, have an elaborate morphology
characterized by a vertical stalk that spans the retina and branches in each retinal layer …
characterized by a vertical stalk that spans the retina and branches in each retinal layer …
Assessment of astrocytes as a mediator of memory and learning in rodents
The classical view of astrocytes is that they provide supportive functions for neurons,
transporting metabolites and maintaining the homeostasis of the extracellular milieu. This …
transporting metabolites and maintaining the homeostasis of the extracellular milieu. This …
Morphometric analysis of astrocytes in brainstem respiratory regions
S SheikhBahaei, B Morris, J Collina… - Journal of …, 2018 - Wiley Online Library
Astrocytes, the most abundant and structurally complex glial cells of the central nervous
system, are proposed to play an important role in modulating the activities of neuronal …
system, are proposed to play an important role in modulating the activities of neuronal …