Innate immune cells, epithelial cells, and many other cell types are capable of detecting
infection or tissue injury, thus mounting regulated immune response. Inflammasomes are …

The inflammasome is a cytoplasmic multiprotein complex responsible for the activation of
inflammatory caspases (caspase-1,-4, and-5) in response to pathogen-and/or damage …

Burkholderia cenocepacia (B. cenocepacia) is an opportunistic bacterium; causing severe
life threatening systemic infections in immunocompromised individuals including cystic …

COVID‐19 has a broad spectrum of clinical manifestations, from asymptomatic or
mild/moderate symptoms to severe symptoms and death. The mechanisms underlying its …

American Tegumentary Leishmaniasis (ATL) is an endemic and neglected disease of South
America. Here, mucosal leishmaniasis (ML) disproportionately affects up to 20% of subjects …

Background IL-1β and TNF-α have been demonstrated as pro-inflammatory cytokines to
participate in the innate immune response and suppression of HBV infection. However, the …

Hepatitis C is considered a major public health problem caused by the hepatitis C virus
(HCV). Viral infections are known to induce production of IL1β through the signaling …

The acute sickness response (ASR) is a stereotyped set of symptoms including fatigue, pain,
and disturbed mood, which are present in most acute infections. The immunological …

Hepatitis C virus (HCV), despite the availability of effective direct-acting antivirals (DAAs)
that clear the virus from> 95% of individuals treated, continues to cause significant health …

OBJECTIVE: COPD is a complex respiratory disease characterized by chronic airway
inflammation and the airflow limitations are not fully reversible due to the combination of …