Plasmodium asexual growth and sexual development in the haematopoietic niche of the host
K Venugopal, F Hentzschel, G Valkiūnas… - Nature Reviews …, 2020 - nature.com
Plasmodium spp. parasites are the causative agents of malaria in humans and animals, and
they are exceptionally diverse in their morphology and life cycles. They grow and develop in …
they are exceptionally diverse in their morphology and life cycles. They grow and develop in …
Vaccines and monoclonal antibodies: new tools for malaria control
K Miura, Y Flores-Garcia, CA Long… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Malaria remains one of the biggest health problems in the world. While significant reductions
in malaria morbidity and mortality had been achieved from 2000 to 2015, the favorable trend …
in malaria morbidity and mortality had been achieved from 2000 to 2015, the favorable trend …
Single-cell RNA sequencing reveals cellular heterogeneity and stage transition under temperature stress in synchronized Plasmodium falciparum cells
The malaria parasite has a complex life cycle exhibiting phenotypic and morphogenic
variations in two different hosts by existing in heterogeneous developmental states. To …
variations in two different hosts by existing in heterogeneous developmental states. To …
The Plasmodium falciparum CCCH zinc finger protein MD3 regulates male gametocytogenesis through its interaction with RNA‐binding proteins
A Farrukh, JP Musabyimana, U Distler… - Molecular …, 2024 - Wiley Online Library
The transmission of malaria parasites to mosquitoes is dependent on the formation of
gametocytes. Once fully matured, gametocytes are able to transform into gametes in the …
gametocytes. Once fully matured, gametocytes are able to transform into gametes in the …
Population genetic analysis of Plasmodium knowlesi reveals differential selection and exchange events between Borneo and Peninsular sub-populations
A Turkiewicz, E Manko, DR Oresegun, D Nolder… - Scientific reports, 2023 - nature.com
The zoonotic Plasmodium knowlesi parasite is a growing public health concern in Southeast
Asia, especially in Malaysia, where elimination of P. falciparum and P. vivax malaria has …
Asia, especially in Malaysia, where elimination of P. falciparum and P. vivax malaria has …
RNA-Seq Analysis Illuminates the Early Stages of Plasmodium Liver Infection
M Toro-Moreno, K Sylvester, T Srivastava, D Posfai… - MBio, 2020 - Am Soc Microbiol
The apicomplexan parasites Plasmodium spp. are the causative agents of malaria, a
disease that poses a significant global health burden. Plasmodium spp. initiate infection of …
disease that poses a significant global health burden. Plasmodium spp. initiate infection of …
Patterns of heterochromatin transitions linked to changes in the expression of Plasmodium falciparum clonally variant genes
L Michel-Todó, C Bancells, N Casas-Vila… - Microbiology …, 2023 - Am Soc Microbiol
The survival of malaria parasites in the changing human blood environment largely depends
on their ability to alter gene expression by epigenetic mechanisms. The active state of …
on their ability to alter gene expression by epigenetic mechanisms. The active state of …
A microtubule-associated protein is essential for malaria parasite transmission
JS Wichers-Misterek, AM Binder, P Mesén-Ramírez… - MBio, 2023 - Am Soc Microbiol
Mature gametocytes of Plasmodium falciparum display a banana (falciform) shape conferred
by a complex array of subpellicular microtubules (SPMT) associated with the inner …
by a complex array of subpellicular microtubules (SPMT) associated with the inner …
PMRT1, a Plasmodium-Specific Parasite Plasma Membrane Transporter, Is Essential for Asexual and Sexual Blood Stage Development
JS Wichers, P Mesén-Ramírez, G Fuchs… - Mbio, 2022 - Am Soc Microbiol
Membrane transport proteins perform crucial roles in cell physiology. The obligate
intracellular parasite Plasmodium falciparum, an agent of human malaria, relies on …
intracellular parasite Plasmodium falciparum, an agent of human malaria, relies on …
Expression patterns of Plasmodium falciparum clonally variant genes at the onset of a blood infection in malaria-naive humans
AK Pickford, L Michel-Todó, F Dupuy, A Mayor… - Mbio, 2021 - Am Soc Microbiol
Clonally variant genes (CVGs) play fundamental roles in the adaptation of Plasmodium
falciparum to fluctuating conditions of the human host. However, their expression patterns …
falciparum to fluctuating conditions of the human host. However, their expression patterns …