Consolidation and maintenance therapy for multiple myeloma after autologous transplantation: where do we stand?

M Mohty, PG Richardson, PL McCarthy… - Bone marrow …, 2015 - nature.com
Novel agents including proteasome inhibitors and immunomodulatory drugs are now
routinely utilized as part of the induction regimen before transplantation and this has …

Optimizing immunomodulatory drug with proteasome inhibitor combinations in newly diagnosed multiple myeloma

I Ntanasis-Stathopoulos, E Terpos… - The Cancer …, 2019 - journals.lww.com
In the modern era of multiple myeloma therapeutics, proteasome inhibitor (PI) and
immunomodulatory drugs (IMiDs) have replaced chemotherapy regimens for newly …

Consolidation therapy with the combination of bortezomib and lenalidomide (VR) without dexamethasone in multiple myeloma patients after transplant: Effects on …

E Terpos, E Kastritis… - American Journal of …, 2019 - Wiley Online Library
Optimizing consolidation treatment in transplant‐eligible newly diagnosed multiple myeloma
patients in order to improve efficacy and bone‐related outcomes is intriguing. We conducted …

Disease monitoring with quantitative serum IgA levels provides a more reliable response assessment in multiple myeloma patients

A Visram, I Vaxman, A S. Al Saleh, H Parmar… - Leukemia, 2021 - nature.com
Abstract Unlike IgG monoclonal proteins (MCPs), IgA MCP quantification is unreliable due to
beta-migration of IgA MCPs on serum protein electrophoresis (SPEP). The utility of …

[HTML][HTML] Clinical relevance of trace bands on serum electrophoresis in patients without a history of gammopathy

TYM Gwathmey, MS Willis, J Tatreau, S Wang… - EJIFCC, 2015 - ncbi.nlm.nih.gov
Serum protein electrophoresis (SPE) and immunofixation is commonly used to screen for
plasma cell dyscrasias. Interpretation of these tests is qualitative by nature and can yield …

The roles of consolidation and maintenance therapy with novel agents after autologous stem cell transplantation in patients with multiple myeloma

M Joks, A Jurczyszyn, M Machaczka… - European Journal of …, 2015 - Wiley Online Library
Novel agents including immunomodulatory drugs and proteasome inhibitors incorporated
into induction regimens and subsequently followed by autologous stem cell transplantation …

A phase I/II study of escalating doses of thalidomide in conjunction with bortezomib and high-dose melphalan as a conditioning regimen for autologous stem cell …

N Biran, SD Rowley, DH Vesole, S Zhang… - Bone marrow …, 2019 - nature.com
A regimen of escalating doses of thalidomide, in combination with bortezomib and high-
dose melphalan (mel/vel/thal), was evaluated as a conditioning regimen for autologous stem …

IFM guidelines on induction and maintenance for patients with newly diagnosed transplant eligible multiple myeloma

M Macro - Hématologie, 2019 - jle.com
For young patients, eligible to high dose therapy, a first line treatment including induction
before and consolidation after peripheral blood stem cells transplant is recommended …

Recommandations de l'Intergroupe francophone du myélome sur le traitement d'induction et l'entretien des patients éligibles au traitement intensif.

M Macro - Hématologie, 2019 - search.ebscohost.com
Chez les sujets jeunes, éligibles au traitement intensif, un traitement d'induction avant
l'autogreffe de cellules souches et un autre, de consolidation, après, sont recommandés en …

Consolidation and Maintenance in De Novo First-Line Multiple Myeloma with Modern Agents

AM Stoppa, D Coso, G Fouquet… - International Journal of …, 2015 - Taylor & Francis
Inclusion of new active drugs, such as IMiDs, proteasome inhibitors and soon the
monoclonal antibodies, in first-line therapy has and will significantly enhance the response …