Neuroimaging genetics approaches to identify new biomarkers for the early diagnosis of autism spectrum disorder

S Nisar, M Haris - Molecular psychiatry, 2023 - nature.com
Autism-spectrum disorders (ASDs) are developmental disabilities that manifest in early
childhood and are characterized by qualitative abnormalities in social behaviors …

Zebrafish modeling of autism spectrum disorders, current status and future prospective

A Tayanloo-Beik, SK Hamidpour, M Abedi… - Frontiers in …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) refers to a complicated range of childhood
neurodevelopmental disorders which can occur via genetic or non-genetic factors. Clinically …

Gene–environment interactions in developmental neurotoxicity: a case study of synergy between chlorpyrifos and CHD8 knockout in human brainspheres

S Modafferi, X Zhong, A Kleensang… - Environmental …, 2021 - ehp.niehs.nih.gov
Background: Autism spectrum disorder (ASD) is a major public health concern caused by
complex genetic and environmental components. Mechanisms of gene–environment (G× E) …

Poly (I: C) alters placental and fetal brain amino acid transport in a rat model of maternal immune activation

ER McColl, M Piquette‐Miller - American Journal of …, 2019 - Wiley Online Library
Problem Maternal immune activation (MIA) during pregnancy is associated with increased
chances of neurodevelopmental disorders including schizophrenia and autism spectrum …

COVID-19 vaccines and the virus: impact on drug metabolism and pharmacokinetics

ER McColl, MA Croyle, WC Zamboni, WG Honer… - Drug Metabolism and …, 2023 - ASPET
This article reports on an American Society of Pharmacology and Therapeutics, Division of
Drug Metabolism and Disposition symposium held at Experimental Biology on April 2, 2022 …

Sex differences in animal models of sodium-valproate-induced autism in postnatal BALB/c mice: whole-brain histoarchitecture and 5-HT2A receptor biomarker …

B Gouda, SN Sinha, M Chalamaiah, V Vakdevi… - Biology, 2022 - mdpi.com
Simple Summary Valproic acid (VPA) is a well-known antiepileptic medication and mood
stabiliser that is frequently prescribed for the treatment of epilepsy, particularly in children …

Comparison of physiological and biochemical autonomic indices in children with and without autism spectrum disorders

R Bharath, SS Moodithaya, SU Bhat, AM Mirajkar… - Medicina, 2019 - mdpi.com
Background and objectives: Autism Spectrum Disorder (ASD) is a complex neuro-
developmental disorder and it has been suggested that symptoms of ASD are associated …

Viral model of maternal immune activation alters placental AMPK and mTORC1 signaling in rats

ER McColl, M Piquette-Miller - Placenta, 2021 - Elsevier
Introduction Maternal immune activation (MIA) is associated with neurodevelopmental
disorders in offspring. We previously demonstrated that poly (I: C)-mediated MIA alters …

Gamma-aminobutyric acid type A receptor variants are associated with autism spectrum disorders

P Adak, N Banerjee, S Sinha… - Journal of Molecular …, 2023 - Springer
Despite several efforts to identify the causes of autism spectrum disorders (ASD), its etiology
remains still unclear. Among other aspects, genes that encode neurotransmitter receptors …

Experimental studies indicate that ST-2223, the antagonist of histamine H3 and dopamine D2/D3 receptors, restores social deficits and neurotransmission …

N Eissa, K Venkatachalam, P Jayaprakash… - Pharmaceuticals, 2022 - mdpi.com
Altered regulation of neurotransmitters may lead to many pathophysiological changes in
brain disorders including autism spectrum disorder (ASD). Given the fact that there are no …