The emerging role of the mammalian glycocalyx in functional membrane organization and immune system regulation
L Möckl - Frontiers in cell and developmental biology, 2020 - frontiersin.org
All cells in the human body are covered by a dense layer of sugars and the proteins and
lipids to which they are attached, collectively termed the “glycocalyx.” For decades, the …
lipids to which they are attached, collectively termed the “glycocalyx.” For decades, the …
Biological roles of glycans
A Varki - Glycobiology, 2017 - academic.oup.com
Simple and complex carbohydrates (glycans) have long been known to play major
metabolic, structural and physical roles in biological systems. Targeted microbial binding to …
metabolic, structural and physical roles in biological systems. Targeted microbial binding to …
“One-pot” protection, glycosylation, and protection–glycosylation strategies of carbohydrates
SS Kulkarni, CC Wang, NM Sabbavarapu… - Chemical …, 2018 - ACS Publications
Carbohydrates, which are ubiquitously distributed throughout the three domains of life, play
significant roles in a variety of vital biological processes. Access to unique and …
significant roles in a variety of vital biological processes. Access to unique and …
IDPi catalysis
L Schreyer, R Properzi, B List - … Chemie International Edition, 2019 - Wiley Online Library
High acidity and structural confinement are pivotal elements in asymmetric acid catalysis.
The recently introduced imidodiphosphorimidate (IDPi) Brønsted acids have met with …
The recently introduced imidodiphosphorimidate (IDPi) Brønsted acids have met with …
A graph neural network model to estimate cell-wise metabolic flux using single-cell RNA-seq data
The metabolic heterogeneity and metabolic interplay between cells are known as significant
contributors to disease treatment resistance. However, with the lack of a mature high …
contributors to disease treatment resistance. However, with the lack of a mature high …
Leloir glycosyltransferases as biocatalysts for chemical production
Glycosylation is a chemical transformation that is centrally important in all glycoscience and
related technologies. Catalysts offering good control over reactivity and selectivity in …
related technologies. Catalysts offering good control over reactivity and selectivity in …
Automated quantification of hydroxyl reactivities: Prediction of glycosylation reactions
The stereoselectivity and yield in glycosylation reactions are paramount but unpredictable.
We have developed a database of acceptor nucleophilic constants (Aka) to quantify the …
We have developed a database of acceptor nucleophilic constants (Aka) to quantify the …
Late-stage C (sp 2)–H and C (sp 3)–H glycosylation of C-aryl/alkyl glycopeptides: mechanistic insights and fluorescence labeling
J Wu, N Kaplaneris, S Ni, F Kaltenhäuser… - Chemical …, 2020 - pubs.rsc.org
C (sp3)–H and C (sp2)–H glycosylations of structurally complex amino acids and peptides
were accomplished through the assistance of triazole peptide-isosteres. The palladium …
were accomplished through the assistance of triazole peptide-isosteres. The palladium …
Advancing discovery of snail mucins function and application
M McDermott, AR Cerullo, J Parziale… - … in bioengineering and …, 2021 - frontiersin.org
Mucins are a highly glycosylated protein family that are secreted by animals for adhesion,
hydration, lubrication, and other functions. Despite their ubiquity, animal mucins are largely …
hydration, lubrication, and other functions. Despite their ubiquity, animal mucins are largely …
Polysaccharide matrices used in 3D in vitro cell culture systems
D Diekjürgen, DW Grainger - Biomaterials, 2017 - Elsevier
Polysaccharides comprise a diverse class of polymeric materials with a history of proven
biocompatibility and continual use as biomaterials. Recent focus on new matrices …
biocompatibility and continual use as biomaterials. Recent focus on new matrices …