Pathogenesis, diagnosis and clinical management of diabetic sensorimotor peripheral neuropathy
G Sloan, D Selvarajah, S Tesfaye - Nature Reviews Endocrinology, 2021 - nature.com
Diabetic sensorimotor peripheral neuropathy (DSPN) is a serious complication of diabetes
mellitus and is associated with increased mortality, lower-limb amputations and distressing …
mellitus and is associated with increased mortality, lower-limb amputations and distressing …
Towards prevention of diabetic peripheral neuropathy: clinical presentation, pathogenesis, and new treatments
MA Elafros, H Andersen, DL Bennett… - The Lancet …, 2022 - thelancet.com
Diabetic peripheral neuropathy (DPN) occurs in up to half of individuals with type 1 or type 2
diabetes. DPN results from the distal-to-proximal loss of peripheral nerve function, leading to …
diabetes. DPN results from the distal-to-proximal loss of peripheral nerve function, leading to …
Pain-resolving immune mechanisms in neuropathic pain
Interactions between the immune and nervous systems are of central importance in
neuropathic pain, a common and debilitating form of chronic pain caused by a lesion or …
neuropathic pain, a common and debilitating form of chronic pain caused by a lesion or …
The IASP classification of chronic pain for ICD-11: chronic neuropathic pain
The upcoming 11th revision of the International Statistical Classification of Diseases and
Related Health Problems (ICD) of the World Health Organization (WHO) offers a unique …
Related Health Problems (ICD) of the World Health Organization (WHO) offers a unique …
Delivering transformative action in paediatric pain: a Lancet Child & Adolescent Health Commission
Executive summary Every infant, child, and adolescent will experience pain at times
throughout their life. Childhood pain ranges from acute to chronic, and includes procedural …
throughout their life. Childhood pain ranges from acute to chronic, and includes procedural …
Pharmacological and non-pharmacological treatments for neuropathic pain: Systematic review and French recommendations
X Moisset, D Bouhassira, JA Couturier, H Alchaar… - Revue …, 2020 - Elsevier
Neuropathic pain remains a significant unmet medical need. Several recommendations
have recently been proposed concerning pharmacotherapy, neurostimulation techniques …
have recently been proposed concerning pharmacotherapy, neurostimulation techniques …
[HTML][HTML] Transcriptional reprogramming of distinct peripheral sensory neuron subtypes after axonal injury
Primary somatosensory neurons are specialized to transmit specific types of sensory
information through differences in cell size, myelination, and the expression of distinct …
information through differences in cell size, myelination, and the expression of distinct …
Microglia in neuropathic pain: cellular and molecular mechanisms and therapeutic potential
Acute nociceptive pain is a key defence system that enables the detection of danger signals
that threaten homeostasis and survival. However, chronic pain (such as the neuropathic …
that threaten homeostasis and survival. However, chronic pain (such as the neuropathic …
Piperidine derivatives: recent advances in synthesis and pharmacological applications
NA Frolov, AN Vereshchagin - International Journal of Molecular Sciences, 2023 - mdpi.com
Piperidines are among the most important synthetic fragments for designing drugs and play
a significant role in the pharmaceutical industry. Their derivatives are present in more than …
a significant role in the pharmaceutical industry. Their derivatives are present in more than …
The neuropathic pain: An overview of the current treatment and future therapeutic approaches
E Cavalli, S Mammana, F Nicoletti… - International journal …, 2019 - journals.sagepub.com
Neuropathic pain is characterized by abnormal hypersensitivity to stimuli (hyperalgesia) and
nociceptive responses to non-noxious stimuli (allodynia). The conditions and the …
nociceptive responses to non-noxious stimuli (allodynia). The conditions and the …