Significance: Oxidative stress is considered to be an important component of various
diseases. A vast number of methods have been developed and used in virtually all diseases …

Vimentin is an intermediate filament protein that plays key roles in integration of cytoskeletal
functions, and therefore in basic cellular processes such as cell division and migration …

Viruses use cell machinery to replicate their genome and produce viral proteins. For this
reason, several intracellular factors, including the redox state, might directly or indirectly …

Astrocyte-neuron interactions protect neurons from iron-mediated toxicity. As dopamine can
be metabolized to reactive quinones, dopaminergic neurons are susceptible to oxidative …

Intermediate filaments are critical for cell and tissue homeostasis and for stress responses.
Cytoplasmic intermediate filaments form versatile and dynamic assemblies that interconnect …

Several recent reviews have suggested a role of oxidative stress in the pathophysiology of
COVID-19, but its interplay with disease severity has not been revealed yet. In the present …

Triggered in response to external and internal ligands in cells and animals, redox
homeostasis is transmitted via signal molecules involved in defense redox mechanisms …

Host-directed therapy using drugs that target cellular pathways required for virus lifecycle or
its clearance might represent an effective approach for treating infectious diseases …

Peroxiredoxin 2 (Prx2) is a thiol protein that functions as an antioxidant, regulator of cellular
peroxide concentrations, and sensor of redox signals. Its redox cycle is widely accepted to …

Redox-mediated signal transduction depends on the enzymatic production of second
messengers such as hydrogen peroxide, nitric oxide and hydrogen sulfite, as well as …