Aging is the greatest risk factor for a multitude of diseases including cardiovascular disease,
neurodegeneration and cancer. Despite decades of research dedicated to understanding …

Background Recently, the hallmarks of aging were updated to include dysbiosis, disabled
macroautophagy, and chronic inflammation. In particular, the low-grade chronic …

Among other mechanisms, oxidative stress has been postulated to play an important role in
the rate of ageing. Oxidative damage contributes to the hallmarks of ageing and essential …

Cardiovascular disease is a leading cause of death and reduced quality of life, proven by
the latest data of the Global Burden of Disease Study, and is only gaining in prevalence …

Oxidative stress in skin plays a major role in the aging process. This is true for intrinsic aging
and even more for extrinsic aging. Although the results are quite different in dermis and …

Reactive oxygen species (ROS) are well-known for playing a dual role as destructive and
constructive species. Indeed, ROS are engaged in many redox-governing activities of the …

The signaling networks that drive the aging process, associated functional deterioration, and
pathologies has captured the scientific community's attention for decades. While many …

Traumatic brain injury (TBI) can lead to disability or devastating consequences with few
established treatments. Although ferroptosis has been shown to be involved in TBI, the …

Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …

We present arguments for an evolution in our understanding of how antioxidants in fruits and
vegetables exert their health-protective effects. There is much epidemiological evidence for …