Cellular mechanisms and physiological consequences of redox-dependent signalling

KM Holmström, T Finkel - Nature reviews Molecular cell biology, 2014 - nature.com
Reactive oxygen species (ROS), which were originally characterized in terms of their
harmful effects on cells and invading microorganisms, are increasingly implicated in various …

Semaphorins and their signaling mechanisms

LT Alto, JR Terman - Semaphorin Signaling: Methods and Protocols, 2017 - Springer
Semaphorins are extracellular signaling proteins that are essential for the development and
maintenance of many organs and tissues. The more than 20-member semaphorin protein …

Role of selenoproteins in redox regulation of signaling and the antioxidant system: a review

Y Zhang, YJ Roh, SJ Han, I Park, HM Lee, YS Ok… - Antioxidants, 2020 - mdpi.com
Selenium is a vital trace element present as selenocysteine (Sec) in proteins that are, thus,
known as selenoproteins. Humans have 25 selenoproteins, most of which are functionally …

Regulation of neuronal development and function by ROS

MCW Oswald, N Garnham, ST Sweeney… - FEBS …, 2018 - Wiley Online Library
Reactive oxygen species (ROS) have long been studied as destructive agents in the context
of nervous system ageing, disease and degeneration. Their roles as signalling molecules …

Mechanisms of actin disassembly and turnover

BL Goode, J Eskin, S Shekhar - Journal of Cell Biology, 2023 - rupress.org
Cellular actin networks exhibit a wide range of sizes, shapes, and architectures tailored to
their biological roles. Once assembled, these filamentous networks are either maintained in …

[HTML][HTML] Oxidation and reduction of actin: Origin, impact in vitro and functional consequences in vivo

C Rouyère, T Serrano, S Frémont, A Echard - European journal of cell …, 2022 - Elsevier
Actin is among the most abundant proteins in eukaryotic cells and assembles into dynamic
filamentous networks regulated by many actin binding proteins. The actin cytoskeleton must …

Regulation of cytoskeletal dynamics by redox signaling and oxidative stress: implications for neuronal development and trafficking

C Wilson, C González-Billault - Frontiers in cellular neuroscience, 2015 - frontiersin.org
A proper balance between chemical reduction and oxidation (known as redox balance) is
essential for normal cellular physiology. Deregulation in the production of oxidative species …

Actin bundles dynamics and architecture

S Rajan, DS Kudryashov, E Reisler - Biomolecules, 2023 - mdpi.com
Cells use the actin cytoskeleton for many of their functions, including their division,
adhesion, mechanosensing, endo-and phagocytosis, migration, and invasion. Actin bundles …

Methionine in proteins: The Cinderella of the proteinogenic amino acids

JC Aledo - Protein Science, 2019 - Wiley Online Library
Methionine in proteins, apart from its role in the initiation of translation, is assumed to play a
simple structural role in the hydrophobic core, in a similar way to other hydrophobic amino …

Semaphorin signalling during development

BC Jongbloets, RJ Pasterkamp - Development, 2014 - journals.biologists.com
Semaphorins are secreted and membrane-associated proteins that regulate many different
developmental processes, including neural circuit assembly, bone formation and …