Gold‐Based Pharmacophore Inhibits Intracellular MYC Protein

S Ofori, S Gukathasan… - Chemistry–A European …, 2021 - Wiley Online Library
Direct targeting of intrinsically disordered proteins, including MYC, by small molecules for
biomedical applications would resolve a longstanding issue in chemical biology and …

Rational Design of Small Molecule Disruptors of Protein-Protein Interactions: PD-1/PD-L1; c-MYC, ARID4B

S Ofori - uknowledge.uky.edu
Protein-protein interactions (PPIs) are vital to many biological processes, including gene
expression, and immune reactions to pathogens. There are approximately 650,000 PPIs in …