Lipid droplets (LDs) contribute to key pathways important for the physiology and
pathophysiology of cells. In a homeostatic view, LDs regulate the storage of neutral lipids …

Lipid droplets (LDs) are ubiquitous, endoplasmic reticulum (ER)-derived organelles that
mediate the sequestration of neutral lipids (eg triacylglycerol and sterol esters), providing a …

Lipid droplets (LDs) are ubiquitous cellular organelles for lipid storage which are composed
of a neutral lipid core bounded by a protein decorated phospholipid monolayer. Although …

Annexins are cytosolic proteins with conserved three-dimensional structures that bind acidic
phospholipids in cellular membranes at elevated Ca2+ levels. Through this they act as Ca2+ …

Cellular metabolism plays a central role in the regulation of both innate and adaptive
immunity. Immune cells utilize metabolic pathways to modulate the cellular differentiation or …

Viruses exploit host cell machinery to support their replication. Defining the cellular proteins
and processes required for a virus during infection is crucial to understanding the …

The vertebrate annexin superfamily (AnxA) consists of 12 members of a calcium (Ca2+) and
phospholipid binding protein family which share a high structural homology. In keeping with …

The formation of stress granules (SGs) is an essential aspect of the cellular response to
many kinds of stress, but its adaptive role is far from clear. SG dysfunction is implicated in …

Cellular communication is essential for effective coordination of biological processes. One
major form of intercellular communication occurs via the release of extracellular vesicles …

The hepatitis C virus (HCV) life cycle is tightly linked to the host cell lipid metabolism with the
endoplasmic reticulum–derived membranous web harboring viral RNA replication …