Garcinia kola: a critical review on chemistry and pharmacology of an important West African medicinal plant
J Tauchen, A Frankova, A Manourova, I Valterova… - Phytochemistry …, 2023 - Springer
Abstract Garcinia kola Heckel (Clusiaceae) is a tree indigenous to West and Central Africa.
All plant parts, but especially the seeds, are of value in local folklore medicine. Garcinia kola …
All plant parts, but especially the seeds, are of value in local folklore medicine. Garcinia kola …
Flavonoids as potential therapeutics in male reproductive disorders
R Mishra, A Nikam, J Hiwarkar, T Nandgude… - Future Journal of …, 2024 - Springer
Background Male infertility presents global challenges, as current drug-based treatments
demonstrate limited effectiveness due to an incomplete understanding of dysfunctions within …
demonstrate limited effectiveness due to an incomplete understanding of dysfunctions within …
Ginkgo biloba supplement abates lead-induced endothelial and testicular dysfunction in Wistar rats via up-regulation of Bcl-2 protein expression, pituitary-testicular …
Background Apoptotic and oxido-inflammatory pathways have been found to be up-
regulated in lead acetate poisoning which has been associated to endothelial and testicular …
regulated in lead acetate poisoning which has been associated to endothelial and testicular …
Epigallocatechin-gallate attenuates rapamycin exacerbated high fat diet-induced autophagy, hormonal dysregulation, testicular and brain oxidative stress, and …
CC Onyekweli, B Ben-Azu, OM Oyovwi… - Food and Chemical …, 2024 - Elsevier
This study investigated whether epigallocatechin-gallate (EGCG) could counteract the
detrimental effects of high-fat diet (HFD)-induced obesity in rats exposed to rapamycin …
detrimental effects of high-fat diet (HFD)-induced obesity in rats exposed to rapamycin …
Kolaviron, a flavonoid‐rich extract ameliorates busulfan‐induced chemo‐brain and testicular damage in male rats through inhibition of oxidative stress, inflammatory …
Previous reports revealed that increased oxidative stress with up‐regulated inflammatory
proteins and apoptotic factors have serious implications in busulfan‐induced chemo‐brain …
proteins and apoptotic factors have serious implications in busulfan‐induced chemo‐brain …
Sitagliptin ameliorates busulfan-induced pulmonary and testicular injury in rats through antioxidant, anti-inflammatory, antifibrotic, and antiapoptotic effects
EA Ali, SG Tayel, MA Abbas - Scientific Reports, 2023 - nature.com
Busulfan (BUS) is an anticancer agent with serious adverse effects on various body organs,
including the lung and testis. Sitagliptin was proven to have antioxidant, anti-inflammatory …
including the lung and testis. Sitagliptin was proven to have antioxidant, anti-inflammatory …
The COMT genetic factor regulates chemotherapy-related prospective memory impairment in survivors with HER2−/+ breast cancer
W Li, Q Zhang, Y Cai, T Chen, H Cheng - Frontiers in Oncology, 2022 - frontiersin.org
Background Previous findings indicated that polymorphism in gene catechol-O-
methyltransferase (COMT) had been linked to chemotherapy-related cognitive impairment …
methyltransferase (COMT) had been linked to chemotherapy-related cognitive impairment …
D-ribose-L-cysteine exhibits restorative neurobehavioral functions through modulation of neurochemical activities and inhibition oxido-inflammatory perturbations in …
Polychlorinated biphenyl (PCB) is potentially harmful environmental toxicant causing
cognitive decline with depressive features. PCB-induced behavioral deficits are associated …
cognitive decline with depressive features. PCB-induced behavioral deficits are associated …
[HTML][HTML] Diosmin alleviates doxorubicin-induced chemobrain in rats via inhibition of oxido-inflammation, apoptosis and modulation of autophagy
Background/aim Doxorubicin (DOX) is a highly effective chemotherapy medicine commonly
used to treat breast cancer; yet, despite its clinical efficacy, it usually causes chemobrain. As …
used to treat breast cancer; yet, despite its clinical efficacy, it usually causes chemobrain. As …
[HTML][HTML] Arjunolic acid reverses fluoxetine-induced alterations in testicular steroidogenic enzymes and membrane bound ionic pump imbalance through suppression …
EO Lynda, NE Kingsley, OM Obukohwo… - JBRA Assisted …, 2024 - ncbi.nlm.nih.gov
Objective The impact of the anti-depressant therapy on gonadal function has been
recognized and discussed over the years. However, data to supplement our understanding …
recognized and discussed over the years. However, data to supplement our understanding …