Colocalization of small-molecule and neuropeptide transmitters is common throughout the
nervous system of all animals. The resulting co-transmission, which provides conjoint …

Highlights•Analysis of small circuits reveals interacting dynamics at different time
scales.•Synaptic and intrinsic properties, neuromodulation, and long-term regulation …

Peptides are the largest and most diverse class of molecules used for neurochemical
communication, playing key roles in the control of essentially all aspects of physiology and …

The crab Cancer borealis nervous system is an important model for understanding neural
circuit dynamics and modulation, but the identity of neuromodulatory substances and their …

Coupled oscillatory circuits are ubiquitous in nervous systems. Given that most biological
processes are temperature-sensitive, it is remarkable that the neuronal circuits of …

Highlights•Mass spectrometry is used to identify and localize neuropeptides across
crustaceans.•Transcriptomics allows peptide and receptor prediction from diverse …

Peptides are known to contribute to central pattern generator (CPG) flexibility throughout the
animal kingdom. However, the role played by receptor diversity/complement in determining …

The crustacean cardiac neuromuscular system is a useful model for studying how neural
circuits generate behavior, as it is comprised of a simple ganglion containing nine neurons …

Although the crustacean heart is modulated by a large number of peptides and amines, few
of these molecules have been localized to the cardiac ganglion itself; most appear to reach …

The southern rock lobster, Jasus edwardsii, is a member of the Achelata native to New
Zealand and southern Australia that in addition to being the subject of an extensive wild …