With the advent of mechanobiology, cell shape and forces have emerged as essential
elements of cell behavior and fate, in addition to biochemical factors such as growth factors …

The field of bioelectronics with the aim to contact cells, cell clusters, biological tissues and
organoids has become a vast enterprise. Currently, it is mainly relying on classical micro …

The mechanisms that regulate the spatial sorting of nonmuscle myosins-2 (NM2) isoforms
and couple them mechanically to the plasma membrane are unclear. Here we show that the …

ABSTRACT S100A11 is a small Ca2+-activatable protein known to localize along stress
fibers (SFs). Analyzing S100A11 localization in HeLa and U2OS cells further revealed …

Externally applied forces, such as those generated through skeletal muscle contraction, are
important to embryonic joint formation, and their loss can result in gross morphologic defects …

Adherent cells use actomyosin contractility to generate mechanical force and to sense the
physical properties of their environment, with dramatic consequences for migration, division …

The emergence of mechanobiology has unveiled complex mechanisms by which cells
adjust intracellular force production to their needs. Most communicable intracellular forces …

The formin INF2 polymerizes a calcium-activated cytoplasmic network of actin filaments,
which we refer to as calcium-induced actin polymerization (CIA). CIA plays important roles in …

The actin cytoskeleton is remarkably adaptable and multifunctional. It often organizes into
nematic bundles such as contractile rings or stress fibers. However, how a uniform and …

Objective We aimed to investigate the effect of empagliflozin on hippocampal
phosphorylated protein levels in obese mice. Materials and methods Sixteen obese mice …