Naloxone dosage for opioid reversal: current evidence and clinical implications

R Rzasa Lynn, JL Galinkin - Therapeutic advances in drug …, 2018 - journals.sagepub.com
Opioid-related mortality is a growing problem in the United States, and in 2015 there were
over 33,000 opioid-related deaths. To combat this mortality trend, naloxone is increasingly …

Are take‐home naloxone programmes effective? Systematic review utilizing application of the Bradford Hill criteria

R McDonald, J Strang - Addiction, 2016 - Wiley Online Library
Abstract Background and Aims Fatal outcome of opioid overdose, once detected, is
preventable through timely administration of the antidote naloxone. Take‐home naloxone …

The effect of overdose education and naloxone distribution: an umbrella review of systematic reviews

A Razaghizad, SB Windle, KB Filion… - … journal of public …, 2021 - ajph.aphapublications.org
Background. Opioids contribute to more than 60 000 deaths annually in North America.
While the expansion of overdose education and naloxone distribution (OEND) programs has …

Opioid overdose rates and implementation of overdose education and nasal naloxone distribution in Massachusetts: interrupted time series analysis

AY Walley, Z Xuan, HH Hackman, E Quinn… - Bmj, 2013 - bmj.com
Objective To evaluate the impact of state supported overdose education and nasal naloxone
distribution (OEND) programs on rates of opioid related death from overdose and acute care …

A systematic review of community opioid overdose prevention and naloxone distribution programs

AK Clark, CM Wilder, EL Winstanley - Journal of addiction …, 2014 - journals.lww.com
Community-based opioid overdose prevention programs (OOPPs) that include the
distribution of naloxone have increased in response to alarmingly high overdose rates in …

Cost-effectiveness of distributing naloxone to heroin users for lay overdose reversal

PO Coffin, SD Sullivan - Annals of internal medicine, 2013 - acpjournals.org
This article has been corrected. The original version (PDF) is appended to this article as a
Supplement. Chinese translation Background: Opioid overdose is a leading cause of …

Opioid agonist treatments and heroin overdose deaths in Baltimore, Maryland, 1995–2009

RP Schwartz, J Gryczynski… - … journal of public …, 2013 - ajph.aphapublications.org
Objectives. We examined the association between the expansion of methadone and
buprenorphine treatment and the prevalence of heroin overdose deaths in Baltimore …

A review of opioid dependence treatment: pharmacological and psychosocial interventions to treat opioid addiction

JC Veilleux, PJ Colvin, J Anderson, C York… - Clinical psychology …, 2010 - Elsevier
Opioid dependence is a problem of national concern, especially with dramatically increased
rates of abuse and dependence of prescription opioids. The current article provides an up-to …

Effectiveness of bystander naloxone administration and overdose education programs: a meta-analysis

RE Giglio, G Li, CJ DiMaggio - Injury epidemiology, 2015 - Springer
The objective of this review was to assess the effectiveness of bystander naloxone
administration and overdose education programs by synthesizing quantitative results …

[PDF][PDF] Community management of opioid overdose

World Health Organization - 2014 - apps.who.int
Opioids are potent respiratory depressants, and overdose is a leading cause of death
among people who use them. Worldwide, an estimated 69 000 people die from opioid …