Blood GFAP as an emerging biomarker in brain and spinal cord disorders
Blood-derived biomarkers for brain and spinal cord diseases are urgently needed. The
introduction of highly sensitive immunoassays led to a rapid increase in the number of …
introduction of highly sensitive immunoassays led to a rapid increase in the number of …
Traumatic brain injuries
Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe.
Mild TBI (the least severe form) is synonymous with concussion and is typically caused by …
Mild TBI (the least severe form) is synonymous with concussion and is typically caused by …
Neurochemical evidence of astrocytic and neuronal injury commonly found in COVID-19
Objective To test the hypothesis that coronavirus disease 2019 (COVID-19) has an impact
on the CNS by measuring plasma biomarkers of CNS injury. Methods We recruited 47 …
on the CNS by measuring plasma biomarkers of CNS injury. Methods We recruited 47 …
Neurochemical signs of astrocytic and neuronal injury in acute COVID-19 normalizes during long-term follow-up
Background Neurologic manifestations are well-recognized features of coronavirus disease
2019 (COVID-19). However, the longitudinal association of biomarkers reflecting CNS …
2019 (COVID-19). However, the longitudinal association of biomarkers reflecting CNS …
Blood biomarkers on admission in acute traumatic brain injury: relations to severity, CT findings and care path in the CENTER-TBI study
Background Serum biomarkers may inform and improve care in traumatic brain injury (TBI).
We aimed to correlate serum biomarkers with clinical severity, care path and imaging …
We aimed to correlate serum biomarkers with clinical severity, care path and imaging …
Assessing the clinical impact of risk prediction models with decision curves: guidance for correct interpretation and appropriate use
The decision curve is a graphical summary recently proposed for assessing the potential
clinical impact of risk prediction biomarkers or risk models for recommending treatment or …
clinical impact of risk prediction biomarkers or risk models for recommending treatment or …
Plasma markers of neurologic injury and inflammation in people with self-reported neurologic postacute sequelae of SARS-CoV-2 infection
MJ Peluso, HM Sans, CA Forman… - Neurology …, 2022 - AAN Enterprises
Background and Objectives The biologic mechanisms underlying neurologic postacute
sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …
sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …
Association between plasma GFAP concentrations and MRI abnormalities in patients with CT-negative traumatic brain injury in the TRACK-TBI cohort: a prospective …
Background After traumatic brain injury (TBI), plasma concentration of glial fibrillary acidic
protein (GFAP) correlates with intracranial injury visible on CT scan. Some patients with …
protein (GFAP) correlates with intracranial injury visible on CT scan. Some patients with …
Fluid biomarkers for mild traumatic brain injury and related conditions
H Zetterberg, K Blennow - Nature reviews neurology, 2016 - nature.com
Diagnostic and prognostic biomarkers for mild traumatic brain injury (TBI), also known as
concussion, remain a major unmet clinical need. Moderate to severe TBI can be diagnosed …
concussion, remain a major unmet clinical need. Moderate to severe TBI can be diagnosed …
Blood biomarkers for traumatic brain injury: a quantitative assessment of diagnostic and prognostic accuracy
Blood biomarkers have been explored for their potential to provide objective measures in
the assessment of traumatic brain injury (TBI). However, it is not clear which biomarkers are …
the assessment of traumatic brain injury (TBI). However, it is not clear which biomarkers are …