The etiologic, theory-based, ontogenetic hierarchical framework of alcohol use disorder: A translational systematic review of reviews.
Abstract Modern nosologies (eg, International Classification of Diseases, 11th edition [ICD-
11], Diagnostic and Statistical Manual of Mental Disorders, 5th edition [DSM–5]) for alcohol …
11], Diagnostic and Statistical Manual of Mental Disorders, 5th edition [DSM–5]) for alcohol …
The genetics of externalizing problems
Externalizing problems generally refer to a constellation of behaviors and/or disorders
characterized by impulsive action and behavioral disinhibition. Phenotypes on the …
characterized by impulsive action and behavioral disinhibition. Phenotypes on the …
A gene-environment cascade theoretical framework of developmental psychopathology.
KK Elam, K Lemery-Chalfant… - … of psychopathology and …, 2023 - psycnet.apa.org
Previous theories have emphasized genetic effects “inside the skin” via endophenotypes
within the broader developmental psychopathology theory. Expanding on the mechanisms …
within the broader developmental psychopathology theory. Expanding on the mechanisms …
Clinical, environmental, and genetic risk factors for substance use disorders: characterizing combined effects across multiple cohorts
Substance use disorders (SUDs) incur serious social and personal costs. The risk for SUDs
is complex, with risk factors ranging from social conditions to individual genetic variation. We …
is complex, with risk factors ranging from social conditions to individual genetic variation. We …
Polygenic risk, family cohesion, and adolescent aggression in Mexican American and European American families: Developmental pathways to alcohol use
Poor family cohesion and elevated adolescent aggression are associated with greater
alcohol use in adolescence and early adulthood. In addition, evocative gene–environment …
alcohol use in adolescence and early adulthood. In addition, evocative gene–environment …
Researchers' perspectives on return of individual genetics results to research participants: a qualitative study
ES Mwaka, DE Sebatta, J Ochieng, IG Munabi… - Global …, 2021 - Taylor & Francis
Genetic results are usually not returned to research participants in Uganda despite their
increased demand. We report on researchers' perceptions and experiences of return of …
increased demand. We report on researchers' perceptions and experiences of return of …
Post‐GWAS in psychiatric genetics: A developmental perspective on the “other” next steps
As psychiatric genetics enters an era where gene identification is finally yielding robust,
replicable genetic associations and polygenic risk scores, it is important to consider next …
replicable genetic associations and polygenic risk scores, it is important to consider next …
Genetic risk of AUDs and childhood impulsivity: examining the role of parenting and family environment
This study examined the independent and interactive effects of genetic risk for alcohol use
disorder (AUD), parenting behaviors, and family environment on childhood impulsivity. Data …
disorder (AUD), parenting behaviors, and family environment on childhood impulsivity. Data …
Age varying polygenic effects on alcohol use in African Americans and European Americans from adolescence to adulthood
Genetic effects on alcohol use can vary over time but are often examined using longitudinal
models that predict a distal outcome at a single time point. The vast majority of these studies …
models that predict a distal outcome at a single time point. The vast majority of these studies …
Genome-wide association study of alcohol dependence in male Han Chinese and cross-ethnic polygenic risk score comparison
Alcohol-related behaviors are moderately heritable and have ethnic-specific characteristics.
At present, genetic studies for alcohol dependence (AD) in Chinese populations are …
At present, genetic studies for alcohol dependence (AD) in Chinese populations are …