[HTML][HTML] Major roles of kupffer cells and macrophages in NAFLD development
Non-alcoholic fatty liver disease (NAFLD) is an important public health problem with growing
numbers of NAFLD patients worldwide. Pathological conditions are different in each stage of …
numbers of NAFLD patients worldwide. Pathological conditions are different in each stage of …
[HTML][HTML] Activation of Kupffer cells in NAFLD and NASH: Mechanisms and therapeutic interventions
GX Xu, S Wei, C Yu, SQ Zhao, WJ Yang… - Frontiers in Cell and …, 2023 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are
emerging as the leading causes of liver disease worldwide. These conditions can lead to …
emerging as the leading causes of liver disease worldwide. These conditions can lead to …
[HTML][HTML] CXCR4-BTK axis mediate pyroptosis and lipid peroxidation in early brain injury after subarachnoid hemorrhage via NLRP3 inflammasome and NF-κB …
C Liu, K Yao, Q Tian, Y Guo, G Wang, P He, J Wang… - Redox Biology, 2023 - Elsevier
CXC chemokine receptor type 4 (CXCR4) is critical for homeostasis of the adaptive and
innate immune system in some CNS diseases. Bruton's tyrosine kinase (BTK) is an essential …
innate immune system in some CNS diseases. Bruton's tyrosine kinase (BTK) is an essential …
Exosomal noncoding RNA-mediated spatiotemporal regulation of lipid metabolism: Implications in immune evasion and chronic inflammation
The hallmark of chronic inflammatory diseases is immune evasion. Successful immune
evasion involves numerous mechanisms to suppress both adaptive and innate immune …
evasion involves numerous mechanisms to suppress both adaptive and innate immune …
[HTML][HTML] The role of matrix metalloproteinase 9 in fibrosis diseases and its molecular mechanisms
Y Wang, L Jiao, C Qiang, C Chen, Z Shen… - Biomedicine & …, 2024 - Elsevier
Fibrosis is a process of tissue repair that results in the slow creation of scar tissue to replace
healthy tissue and can affect any tissue or organ. Its primary feature is the massive …
healthy tissue and can affect any tissue or organ. Its primary feature is the massive …
[HTML][HTML] Macrophages and the development and progression of non-alcoholic fatty liver disease
B Alabdulaali, F Al-Rashed, M Al-Onaizi… - Frontiers in …, 2023 - frontiersin.org
The liver is the site of first pass metabolism, detoxifying and metabolizing blood arriving from
the hepatic portal vein and hepatic artery. It is made up of multiple cell types, including …
the hepatic portal vein and hepatic artery. It is made up of multiple cell types, including …
[HTML][HTML] Interorgan communication with the liver: novel mechanisms and therapeutic targets
J Zhao, X Zhang, Y Li, J Yu, Z Chen, Y Niu… - Frontiers in …, 2023 - frontiersin.org
The liver is a multifunctional organ that plays crucial roles in numerous physiological
processes, such as production of bile and proteins for blood plasma, regulation of blood …
processes, such as production of bile and proteins for blood plasma, regulation of blood …
[HTML][HTML] Mesenchymal stem cells and their derived exosomes for ALI/ARDS: a promising therapy
D Liang, C Liu, M Yang - Heliyon, 2023 - cell.com
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a serious clinical
syndrome with a high morbidity and mortality. Presently, therapeutic approaches for …
syndrome with a high morbidity and mortality. Presently, therapeutic approaches for …
[HTML][HTML] Exosome-Mediated Impact on Systemic Metabolism
K Cunha e Rocha, W Ying… - Annual Review of …, 2024 - annualreviews.org
Exosomes are small extracellular vesicles that carry lipids, proteins, and microRNAs
(miRNAs). They are released by all cell types and can be found not only in circulation but in …
(miRNAs). They are released by all cell types and can be found not only in circulation but in …
In silico and in vivo demonstration of the regulatory mechanism of Qi-Ge decoction in treating NAFLD
C Peng, J Li, X Ke, F Liu, K Huang - Annals of medicine, 2023 - Taylor & Francis
Background Nonalcoholic fatty liver disease (NAFLD), a chronic and progressive liver
disease, often causes steatosis and steatohepatitis. Qi-Ge decoction (QGD) shows a good …
disease, often causes steatosis and steatohepatitis. Qi-Ge decoction (QGD) shows a good …