Calcium ions aggravate Alzheimer's disease through the aberrant activation of neuronal networks, leading to synaptic and cognitive deficits

PP Guan, LL Cao, Y Yang, P Wang - Frontiers in molecular …, 2021 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disease that is characterized by the
production and deposition of β-amyloid protein (Aβ) and hyperphosphorylated tau, leading …

Adenosine A2B receptors differently modulate oligodendrogliogenesis and myelination depending on their cellular localization

F Cherchi, M Venturini, G Magni, L Frulloni, M Chieca… - Glia, 2024 - Wiley Online Library
Differentiation of oligodendrocyte precursor cells (OPCs) into mature oligodendrocytes (OLs)
is a key event for axonal myelination in the brain; this process fails during demyelinating …

NIR laser photobiomodulation induces neuroprotection in an in vitro model of cerebral hypoxia/ischemia

E Gerace, F Cialdai, E Sereni, D Lana, D Nosi… - Molecular …, 2021 - Springer
Brain photobiomodulation (PBM) is an innovative treatment for a variety of neurological
conditions, including cerebral ischemia. However, the capability of PBM for ischemic stroke …

Animal models for studies of alcohol effects on the trajectory of age-related cognitive decline

TC Foster - Alcohol, 2023 - Elsevier
There is growing interest in understanding how ethanol use interacts with advancing age to
influence the brain and cognition. Animal models are employed to investigate the cellular …

[HTML][HTML] Antidepressant-induced increase in GluA2 expression does not translate in changes of AMPA receptor-mediated synaptic transmission at CA3/CA1 synapses …

E Gerace, L Polenzani, M Magnani, E Zianni… - …, 2023 - Elsevier
Chronic treatment with serotonin selective reuptake inhibitors or tryciclic antidepressant
drugs in rodents has been shown to increase the expression of GluA1 and/or GluA2 AMPA …

AMPAkine CX516 alleviated chronic ethanol exposure-induced neurodegeneration and depressive-like behavior in mice

H Yao, D Zhang, H Yu, H Shen, X Lan, H Liu… - Toxicology and Applied …, 2022 - Elsevier
Chronic ethanol exposure (CEE) is associated with greater neurodegenerative effects and
an increased risk of depression disorder. The AMPAR is thought to be involved in …

[HTML][HTML] Prenatal ethanol exposure impairs hippocampal plasticity and cognition in adolescent mice

L Curti, B Rizzi, F Mottarlini, E Bigagli, A Ilari… - Progress in Neuro …, 2025 - Elsevier
Background Prenatal alcohol exposure (PAE) induces a wide range of neurodevelopmental
disabilities that are grouped under the term 'fetal alcohol spectrum disorders'(FASD). The …

Changes of Oxidative Stress-Related Gene Expression in an in vitro Model of Neonatal Hypoxic-Ischemic Encephalopathy

C Dani, S Pratesi, G Ranieri, G Mannaioni, E Gerace - Neonatology, 2022 - karger.com
Background: We recently demonstrated that oxygen-glucose deprivation (OGD) and
unconjugated bilirubin (UCB) can damage mature and immature organotypic hippocampal …

[HTML][HTML] Ethanol-induced AMPA alterations are mediated by mGLU5 receptors through miRNA upregulation in hippocampal slices

E Gerace, L Curti, L Caffino, E Bigagli… - European Journal of …, 2023 - Elsevier
Prenatal alcohol exposure (PAE) affects neuronal networks and brain development causing
a range of physical, cognitive and behavioural disorders in newborns that persist into …

Proteomics and weighted gene correlated network analysis reveal glutamatergic synapse signaling in diazepam treatment of alcohol withdrawal

W Kong, S Huang, Z Chen, X Li, S Liu… - Frontiers in …, 2023 - frontiersin.org
Background: Alcohol use disorder (AUD) is characterized by chronic excessive alcohol
consumption, often alternating with periods of abstinence known as alcohol withdrawal …