How are individual cell behaviors coordinated toward invariant large-scale anatomical
outcomes in development and regeneration despite unpredictable perturbations …

A critical aspect of evolution is the layer of developmental physiology that operates between
the genotype and the anatomical phenotype. While much work has addressed the evolution …

Bioengineering can address many important needs, from transformative biomedicine to
environmental remediation. In addition to practical applications, the construction of new …

The central nervous system (CNS) underlies memory, perception, decision-making, and
behavior in numerous organisms. However, neural networks have no monopoly on the …

We propose and present converging evidence for the Cytoelectric Coupling Hypothesis:
Electric fields generated by neurons are causal down to the level of the cytoskeleton. This …

Each of us made the remarkable journey from mere matter to mind: starting life as a
quiescent oocyte (“just chemistry and physics”), and slowly, gradually, becoming an adult …

It is well known that electrical signals are deeply associated with living entities. Much of our
understanding of excitable tissues is derived from studies of specialized cells of neurons or …

Regeneration capacity declines with age, but why juvenile organisms show enhanced tissue
repair remains unexplained. Lin28a, a highly conserved RNA-binding protein expressed …

The ability to control pattern formation is critical for the both the embryonic development of
complex structures as well as for the regeneration/repair of damaged or missing tissues and …

What determines large-scale anatomy? DNA does not directly specify geometrical
arrangements of tissues and organs, and a process of encoding and decoding for …