Downstream processing needs more innovative ideas to advance and overcome current
bioprocessing challenges. Chromatography is by far the most prevalent technique used by a …

Lysozyme is an antimicrobial peptide with a high enzymatic activity and positive charges.
Therefore, it has applications in food and pharmaceutical industries as an antimicrobial …

Abstract Lysozyme (EC 3.2. 1.17) is a glycoside hydrolase with an important role in
antibacterial defense mechanism. Because of its bactericidal and bacteriostatic properties …

Properties of magnetic suspensions depend on the fluid, the particles and the magnetic
background field. The simulation is aimed at understanding the influence of magnetic …

Once a therapeutic protein has been produced by a chosen production system, the product
must be separated and recovered from the host system. Cell harvest and recovery serve this …

High-Gradient Magnetic Filtration (HGMF) uses heavy electromagnets or c-shaped type
permanent magnets in order to generate a magnetic field. When using electromagnets …

Magnetically Enhanced Centrifugation is a hybrid method combining the advantages of
magnetic separation and centrifugation. Magnetic particles are separated due to magnetic …

Biopharmaceuticals, medicines made by or from living organisms (including cells from living
organisms), are extremely effective in treating a broad range of diseases. Their importance …

Despite ongoing progress in nano-and biomaterial sciences, large-scale bioprocessing of
nanoparticles remains a great challenge, especially because of the difficulties in removing …

Proteins and in particular pharmaceutical proteins like monoclonal antibodies are expensive
products. Protein crystallization is an interesting alternative process step to the common …