Simple Summary The cellular mechanisms of drug resistance prevent the correct efficacy of
the therapies used in various types of cancer and nanotechnology has been postulated as a …

A significant obstacle to treating cancer is multidrug resistance (MDR), which is the capacity
of cancerous cells to develop resistance to both traditional and cutting-edge …

PhenolaTi is a promising Ti (IV) anticancer complex, with high stability and cytotoxicity,
without notable toxic side-effects. Its cellular mechanism was proposed to relate to ER …

Highly thermal stable dithiophenolato Ti (IV)-chitosan nanocomposite (DBT-CS) was formed
from dithiophenolato Ti (IV)-complex (DBT) and chitosan (CS) nanoparticles. As DNA-drugs …

Titanium (IV) coordination complexes represent attractive alternatives to platinumbased
anticancer drugs. The advantage of the titanium metal lies in its low toxicity, and the …

Octahedral titanium (IV) complexes of phenolato hexadentate ligands were developed and
showed very high stability for days in water solutions. In vitro cytotoxicity studies showed …

Vanadium (V) oxo complexes with no labile ligands, including six octahedral complexes with
pentadentate diaminotris (phenolato) ligands and one pentacoordinate complex with a …

Due to the toxicity of platinum compounds used in the clinic as anticancer chemotherapies,
titanium serves as a safe and attractive alternative. Lately, we introduced a new family of Ti …

Two differently substituted fluorescent salen Ti (IV) complexes were developed. One was
inactive on human cancer cells, whereas the other showed high cytotoxicity. Based on live …

Titanocene dichloride and budotitane have opened a new chapter in medicinal chemistry of
titanium (IV) complexes being novel non-platinum antitumor metallic agents. Numerous …