Advances in nanoparticle (NP) production and demand for control over nanoscale systems
have had significant impact on tissue engineering and regenerative medicine (TERM). NPs …

Intervertebral disc (IVD) degeneration may cause many diseases and pain. Stem cell
migration toward the site of IVD degeneration is a key factor for IVD regeneration. In the …

Polymer hydrogels intended for use in bone repair need to be strong, elastic, and capable of
enduring degradation. However, many natural polymer hydrogels lack these essential …

Abstract Purpose of Review Intervertebral disc degeneration is the primary etiology of low
back pain and radicular pain. This review examines the roles of crucial chemokines in …

This work aims to design biocompatible aerogel sponges that can host and control the
release of stromal cell-derived factor-1α (SDF-1α or CXCL12), a key protein for applications …

This interdisciplinary research highlights the engineering of glycolipid nanomicelles with
surface modification using a BBB crossing peptide for in vivo drug delivery especially for …

Inhibition of tumor growth and metastasis simultaneously is an important issue for tumor
therapy. The CXCR4/CXCL12 axis plays a crucial role in cancer metastasis, and the …

In order to provide best control of the regeneration process for each individual patient, the
release of protein drugs administered during surgery may need to be timely adapted and/or …

Chemotaxis enables cellular communication and movement within the body. This review
focuses on exploiting chemotaxis as a tool for repair of the central nervous system (CNS) …

Introduction Stromal cell derived factor-1a (SDF-1a) and its receptor CXCR4 modulate stem
cell recruitment to neural injury sites. SDF-1a gradients originating from injury sites …