Histogenesis of intracranial germ cell tumors: primordial germ cell vs. embryonic stem cell

EL Burnham, T Tomita - Child's Nervous System, 2023 - Springer
Introduction Intracranial germ cell tumor (iGCT) is a rare disorder and often occurs during
childhood and adolescence. iGCTs are frequently localized in pineal region and …

Direct reprogramming of human Sertoli cells into male germline stem cells with the self-renewal and differentiation potentials via overexpressing DAZL/DAZ2/BOULE …

W Zhang, W Chen, Y Cui, L Wen, Q Yuan, F Zhou… - Stem cell reports, 2021 - cell.com
We propose a new concept that human somatic cells can be converted to become male
germline stem cells by the defined factors. Here, we demonstrated that the overexpression of …

TET1 facilitates specification of early human lineages including germ cells

FM Hsu, QY Wu, EB Fabyanic, A Wei, H Wu, AT Clark - Iscience, 2023 - cell.com
Summary Ten Eleven Translocation 1 (TET1) is a regulator of localized DNA demethylation
through the conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). To …

[PDF][PDF] Defining the essential regulators of naive human pluripotent stem cell reprogramming

A Bendall - 2022 - repository.cam.ac.uk
Human pluripotent stem cells (PSCs) exist in two distinct states–naïve and primed, which are
interconvertible. Naïve PSCs uniquely harbour several desirable properties that primed …

[引用][C] TET1 facilitates specification of early human lineages including germ cells

HW Wei, AT Clark - europepmc.org
SUMMARY Ten Eleven Translocation 1 (TET1) is a regulator of localized DNA
demethylation through the conversion of 5-methylcytosine (5mC) to 5 …