Tools and techniques for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/COVID-19 detection
SUMMARY The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and …
respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and …
Historical perspective on the discovery of the quasispecies concept
E Domingo, C García-Crespo… - Annual review of …, 2021 - annualreviews.org
Viral quasispecies are dynamic distributions of nonidentical but closely related mutant and
recombinant viral genomes subjected to a continuous process of genetic variation …
recombinant viral genomes subjected to a continuous process of genetic variation …
Nucleocapsid mutations R203K/G204R increase the infectivity, fitness, and virulence of SARS-CoV-2
Previous work found that the co-occurring mutations R203K/G204R on the SARS-CoV-2
nucleocapsid (N) protein are increasing in frequency among emerging variants of concern …
nucleocapsid (N) protein are increasing in frequency among emerging variants of concern …
SARS-CoV-2 quasispecies provides an advantage mutation pool for the epidemic variants
F Sun, X Wang, S Tan, Y Dan, Y Lu, J Zhang… - Microbiology …, 2021 - Am Soc Microbiol
The dynamics of quasispecies afford RNA viruses a great fitness on cell tropism and host
range. To study the quasispecies features and the intra-host evolution of SARS-CoV-2, we …
range. To study the quasispecies features and the intra-host evolution of SARS-CoV-2, we …
Incipient functional SARS-CoV-2 diversification identified through neural network haplotype maps
S Delgado, P Somovilla, C Ferrer-Orta… - Proceedings of the …, 2024 - National Acad Sciences
Since its introduction in the human population, SARS-CoV-2 has evolved into multiple
clades, but the events in its intrahost diversification are not well understood. Here, we …
clades, but the events in its intrahost diversification are not well understood. Here, we …
Mortality in individuals treated with COVID-19 convalescent plasma varies with the geographic provenance of donors
KL Kunze, PW Johnson, N van Helmond… - Nature …, 2021 - nature.com
Successful therapeutics and vaccines for coronavirus disease 2019 (COVID-19) have
harnessed the immune response to severe acute respiratory syndrome coronavirus 2 (SARS …
harnessed the immune response to severe acute respiratory syndrome coronavirus 2 (SARS …
SARS-CoV-2 variants identification: overview of molecular existing methods
Since the beginning of COVID-19 pandemic the Real Time sharing of genome sequences of
circulating virus supported the diagnostics and surveillance of SARS-CoV-2 and its …
circulating virus supported the diagnostics and surveillance of SARS-CoV-2 and its …
New insights into the physiopathology of COVID-19: SARS-CoV-2-associated gastrointestinal illness
Although SARS-CoV-2 is considered a lung-tropic virus that infects the respiratory tract
through binding to the ACE2 cell-surface molecules present on alveolar lungs epithelial …
through binding to the ACE2 cell-surface molecules present on alveolar lungs epithelial …
Point mutations at specific sites of the nsp12–nsp8 interface dramatically affect the RNA polymerization activity of SARS-CoV-2
C Ferrer-Orta, S Vázquez-Monteagudo… - Proceedings of the …, 2024 - pnas.org
In a recent characterization of the Severe Acute Respiratory Syndrome Coronavirus 2
(SARS-CoV-2) variability present in 30 diagnostic samples from patients of the first COVID …
(SARS-CoV-2) variability present in 30 diagnostic samples from patients of the first COVID …
Quasispecies nature of RNA viruses: lessons from the past
Viral quasispecies are distinct but closely related mutants formed by the disparity in viral
genomes due to recombination, mutations, competition, and selection pressure. Theoretical …
genomes due to recombination, mutations, competition, and selection pressure. Theoretical …